PK​/PD Senior Scientist

POSITION RESPONSIBILITIES:

• Design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
• Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
• Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects.
• Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid translation, measurement of target engagement, and dose regimen predictions.
• Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with project direction.
• Present research results to scientific teams, management, and regulatory agencies.
• Write sections of regulatory submissions, respond to regulatory inquiries, and maintain knowledge of regulatory guidance.

• Ph.D. in pharmacology, pharmaceutical sciences, biochemistry, or related field.
• 2–4 years post-doctoral experience in pharmaceutical development is highly desirable; DVM DACVCP or DVM Dipl. ECVPT is highly desirable.
• Proven ability to design, analyze, and interpret in vivo PK and PK/PD studies; biotherapeutics (protein therapeutics) experience is highly desirable.

• Proficiency with PK/PKPD analysis software such as Win Nonlin, Monolix, or Watson.
• Excellent verbal and written communication.
• Self-starter who can prioritize and work efficiently with minimal supervision.
• Working knowledge of bioanalytical methodology.
• PK/PD modeling and simulation (PBPK, QSP, population PK using NONMEM, R, or related) is highly desirable.

• US base salary range: $114,000–$185,000; eligible for short-term and long-term incentives.
• Healthcare/insurance beginning day one, 401(k) match and profit-sharing, and 4 weeks vacation.
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