Post Doctoral Research Associate Job Dover area,Delaware USA,Research/Development

The Post-Doctoral Associate will work closely with the Principal Investigator using biochemical and molecular biology techniques to develop targeted small protein therapeutics that aim to induce an immune response by targeting specific proteins in cancer cells.

Functions

Carry out experiments to develop and validate small proteins that have high affinity and selectivity for cancer cells.

Assist with preparation of manuscripts for submission to scientific journals and conferences.

Perform literature studies and write technical reports.

Assist in training and mentoring lab personnel, including graduate and undergraduate students.

Organize and attend research group and sub-group meetings.

Other Functions

Oversee image analysis projects and work with other lab members.

Present the lab’s research work at regional, national, and international scientific meetings and conferences.

Attend workshops/seminars on protein engineering and discovery.

Attend workshops/seminars on computational aided drug discovery.

Required Knowledge, Skills, and Abilities

Demonstrated experience in protein engineering, expression, purification, and biochemical characterization.

Demonstrated experience in cell-based assays such as ELISA, flow cytometry binding, BLI.

Expertise in molecular biology techniques such as cloning, PCR, mutagenesis, DNA extraction, gel electrophoresis.

Knowledge of protein/antibody discovery and optimization using in vitro display (such as phage or yeast) technology.

Knowledge of two-hybrid assay screening, focusing on studying molecular interactions, such as protein-protein, protein-DNA, and protein-RNA interactions.

Strong analytical and problem-solving skills.

Excellent communication and collaborative abilities.

Works well as part of a diverse, multicultural team.

Education and Experience

PhD (required) in Chemistry, Biochemistry, Biology, Molecular Biology or related area.

Experience in expression, purification, characterization and optimization of recombinant proteins.

Experience with design, execute, and troubleshoot SPR and BLI-based assays, including binding kinetics, blocking, affinity, competition, and epitope binning.

Other Preferences

Familiarity with de novo protein design.

The criteria for evaluation in this position include, but are not limited to, the following:

Demonstrates knowledge of the DSU Fundamentals.

Demonstrates ability to manage day-to-day operations of the project per directives of PI.

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