Research Associate II Hope Duarte, CA

Research Associate II – City of Hope, Duarte, CA

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we are changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our dedicated faculty and staff are driven by a common mission: contributing to innovative approaches in predicting, preventing, and curing diseases, and shaping the future of medicine through cutting‑edge research.

A Research Associate II position is available in the laboratory of Dr. Melanie Shapiro, PhD, in the AR‑DMRI Department of Diabetes Immunology. You will perform a variety of experiments related to the genetics and immunology of type 1 diabetes.

The Shapiro laboratory studies germ‑line genetic variants predicting response to immunotherapies for type 1 diabetes, as well as somatic variants in the pancreas and immune cells of organ donors with type 1 diabetes.

• Isolate and culture immune cells in vitro
• Perform CRISPR/Cas9‑mediated gene editing
• Run multicolor flow cytometry and analysis
• Execute ELISA and/or multiplex cytokine quantification assays
• Analyze single nucleotide polymorphism genotyping data
• Perform murine injections, dissection, and processing of pancreas and immune organs for in vivo experiments
• Process and analyze single‑cell RNA sequencing data

• Bachelor’s degree (master’s degree preferred)
• 2+ years of related research/laboratory experience with a bachelor’s degree, or 1+ year with a master’s degree
• Some experience in the experimental and analytical techniques listed above is preferred, but not required

City of Hope employees’ pay is based on work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.