Staff Scientist - Hematologic Malignancies

Join the forefront of groundbreaking research at City of Hope
, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting‑edge research.

• Design and execute experiments involving genetically engineered mouse models, patient‑derived samples, and molecular assays, including DNA/RNA sequencing, immunohistochemistry, and flow cytometry.
• Develop and optimize laboratory protocols for studying disease mechanisms, biomarker discovery, and diagnostic refinement in hematologic malignancies.
• Analyze and interpret experimental data using appropriate computational tools and collaborate with bioinformatics staff when necessary.
• Troubleshoot laboratory equipment (e.g., flow cytometers, sequencers) and coordinate routine maintenance and quality control.
• Work collaboratively with team members to design experiments, interpret findings, and contribute to manuscript and grant preparation.
• Communicate experimental results clearly to faculty, trainees, and clinical collaborators; contribute to team meetings and project planning.
• Provide mentorship and training to junior lab members on experimental design, execution, and data analysis.
• Maintain meticulous and organized records of all experiments and ensure proper documentation for data reproducibility.
• Adhere to institutional and laboratory safety regulations and compliance standards for working with human samples and animal models.

• PhD, MD, or MD/PhD degree in a relevant biomedical field (or commensurate experience) with a minimum of 3 years of hands‑on experience in a clinical or research laboratory focused on hematologic malignancies, molecular pathology, or flow cytometry.
• Demonstrated expertise in data analysis and immunophenotyping; experience with cell sorting is highly desirable.
• Proven ability to design and execute experiments using mouse models, primary human samples, and genomic profiling tools (e.g., NGS, RNA‑seq).
• Demonstrated leadership in mentoring junior staff and managing laboratory operations.

City of Hope is an equal opportunity employer.