Executive Director, Global Safety Strategy & Risk Management

Executive Director, Global Safety Strategy & Benefit-Risk Management

We are seeking an exceptional physician leader to join our Global Patient Safety organization. This role will provide strategic leadership for the scientific evaluation of product safety, benefit risk assessment, pharmacovigilance strategy, and global safety governance across the United Therapeutics Pulmonary portfolio. The ideal candidate is a strategic and influential safety leader with deep expertise in pharmacovigilance, clinical medicine, benefit-risk evaluation, regulatory science, and safety governance.

This person will exercise substantial independent judgement in evaluating complex scientific and regulatory issues, balancing patient safety with business objectives, and influencing executive decisions with potential global regulatory impact.

The Executive Director is responsible for establishing and executing the enterprise's safety strategy supporting investigational and marketed products throughout the product lifecycle. This includes oversight of Brand Safety Leads/Medical Safety Physicians while ensuring scientifically robust safety surveillance, signal evaluation, regulatory compliance, and benefit risk management across all pulmonary portfolio, devices, biologics, combination products, and innovative development programs.

As a recognized subject matter expert, the Executive Director collaborates extensively with Clinical Development, Regulatory Affairs, Medical Affairs, Biostatistics, Epidemiology, Quality, Commercial, Legal, Alliance Management, and Global Patient Safety Operations to influence critical business decisions that impact patient safety, regulatory strategy, and product development.

Minimum Requirements:

• MD
• 10+ years of leading Safety Risk Management organization in pharma or biopharma
• 3+ years of managing other MDs or sub investigators
• 5+ years of clinical trial support, either as a principal investigator or sub investigator or development team membership
• 3+ years of experience working in a matrix team environment, including supporting other team members when required
• Ability to promote collegiality and teamwork among peers, working in a matrix environment
• Proficient with MS Office suite (Word, Excel, Outlook, PowerPoint)
• Data analytics experience with tools, such as Excel, patient listing reviews, dashboards, Spotfire, Qlik View etc.
• Ability to search wide range or literature and clinical sources to collect evidence-based data & synthesis solid clinical conclusions
• Excellent oral and written communication skills to support responses to Health Authority requests
• Excellent interpersonal and time management skills, to ensure compliance with firm timelines
• Ability to think strategically, outside of the box and present independent, reasoned solutions to identified safety issues & minimizing risk to patients within the program or commercial therapy
• Ability to influence internal & external stakeholders, reach consensus, and meet critical regulatory, safety & business objectives
• Demonstrated problem solving skills that enact change and drive continuous improvement
• Ability to be flexible, adaptable, and open minded in a constantly changing environment
• Ability to build and manage cross-functional relationships by motivating and inspiring others
• Proactive, self-starter with ability to work under minimal direction

Preferred Qualifications:

• MD Pulmonology Specialty, USA practice and Board Certification
• 3+ years of Clinical/Medical practice experience within the US and/or full registration with a medical licensing body
• MD
  - Physician
  - State Licensure

Job Location and Travel:

United Therapeutics has the flexibility to have this position based out of our RTP, NC office on a hybrid schedule, or located remotely in the continental United States. Relocation assistance may be available for non-local candidates. This position may travel up to 15%.

The salary range for this position is $275,000 - $375,000 per year and reflects our good-faith estimate of the compensation for this role at the time of posting. An employee's position within the salary range will be based on factors such as education, qualifications, experience, skills, geographic location, and business needs, as well as other factors permitted by law at the time of posting.

This range may be modified in the future based on company and market factors.

Eligible employees may participate in the Company's comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit

United Therapeutics Corporation is an Equal Opportunity Employer, including veterans and individuals with disabilities. We strive to be an organization that engages the minds, hearts, and most spirited efforts of each of our employees. Our sense of purpose transforms what we do from work into mission,…