Equipment Engineer Sat - Tue

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi‑disciplinary organization of scientists, engineers, and physicians and we are using the power of next‑generation sequencing (NGS), population‑scale clinical studies, and state‑of‑the‑art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit

The Equipment Engineer I contributes professional engineering support to the evaluation, installation, modification, and maintenance of manufacturing equipment to ensure reliable, efficient, and compliant operation. Operating within a professional scope, this role applies foundational engineering principles to assess equipment performance, support technical problem‑solving, and participate in improvement initiatives that strengthen equipment reliability and operational consistency. The position collaborates with engineers, technicians, and cross‑functional partners to advance technical solutions, maintain engineering documentation, and contribute to the effective execution of equipment engineering activities.

You will work on‑site full‑time at our office located in Durham, NC.

This position works the weekend shift, Sat - Tue from 6:00am to 4:00pm.

• Performs engineering analyses by collecting data, reviewing operational trends, and preparing technical observations to support evaluations of equipment performance and reliability.

• Supports professional engineering activities related to installation, modification, and qualification of manufacturing equipment, ensuring alignment with established engineering standards and production requirements.

• Executes advanced maintenance, repair, and technical adjustments on complex manufacturing equipment by applying extensive procedural knowledge and hands‑on expertise.

• Contributes to equipment troubleshooting efforts by applying engineering principles to initial assessments and collaborating on the development of corrective actions and process improvements.

• Develops and maintains engineering documentation, including specifications, change records, technical instructions, and performance logs, ensuring accuracy and compliance with engineering controls.

• Collaborates with engineers, maintenance personnel, and operations teams on continuous improvement initiatives that enhance equipment capability, efficiency, and reliability.

• Participates in equipment testing, calibration, and verification activities to support engineering evaluations and adherence to technical standards.

• Applies professional judgment within defined engineering procedures while upholding safety, quality, and regulatory requirements in all aspects of equipment engineering support.

• These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

• Bachelor’s degree in mechanical engineering, electrical engineering, manufacturing engineering, or a related technical discipline.

• 0–2 years of relevant engineering experience, preferably in a manufacturing or production environment.

• Basic understanding of mechanical, electrical, pneumatic, and control systems.

• Familiarity with CAD tools, technical drawings, and engineering documentation.

• Knowledge of root cause analysis methods and problem‑solving techniques is preferred.

• Demonstrated level of knowledge regarding applicable regulatory standards commensurate with the position’s complexity and scope, contributing to organizational regulatory compliance. Minimal applicable standards for this position include:

  • GMP quality management systems (e.g., ISO 13485)

  • Clinical laboratory…