Director, Engineering

Overview

OXB is a quality and innovation-led viral vector CDMO with a mission to enable clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, AAV, and adenoviral vectors.

OXB's world-class capabilities span from early-stage development to commercialisation, supported by robust QA systems, analytical methods, and depth of regulatory expertise.

Durham, NC, US

Director, Engineering – lead engineering across Validation, Automation, and Process Engineering to ensure reliable, compliant, and scalable manufacturing operations. You will be part of the Durham Leadership Team and play a key role in advancing our mission.

• Lead and develop a high-performing Engineering function across Validation, Automation, Process Engineering, and Engineering Operations.
• Own end-to-end engineering execution, including CQV, automation systems, process engineering, and equipment lifecycle management.
• Deliver capital engineering programmes (facility upgrades, installations, and expansion) on time, within scope, and on budget.
• Drive engineering strategy and performance to enhance manufacturing reliability, efficiency, compliance, and capacity.
• Ensure robust validation and automation frameworks, supporting cGMP compliance, data integrity, and inspection readiness.
• Partner cross-functionally to support manufacturing, technical transfer, and scale-up, enabling operational readiness and site growth.

• Bachelor’s degree in Engineering, Chemical Engineering, Mechanical Engineering, Electrical Engineering, Bioprocess Engineering, or related technical discipline required; advanced degree preferred.
• Extensive leadership experience (15+ years) in biopharma, biologics, or advanced manufacturing environments.
• Proven leadership across Validation, Automation, and Process Engineering, with experience building and leading high-performing teams.
• Strong cGMP expertise, including regulatory inspection readiness and compliance within biologics or advanced therapy manufacturing.
• Deep technical knowledge of CQV and engineering systems, including lifecycle validation, equipment qualification, and compliance programmes.
• Hands-on experience with automation and manufacturing technologies, such as PLC/SCADA, process controls, and digital manufacturing systems.
• Track record of delivering capital projects and supporting scale-up, technical transfer, and operational readiness within complex or high-growth environments.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

• Competitive total reward packages
• Wellbeing programs that support your mental and physical health
• Career development opportunities to help you grow and thrive
• Supportive, inclusive, and collaborative culture
• State-of-the-art labs and manufacturing facilities
• A company that lives its values:
  Responsible, Responsive, Resilient, Respect

Nearest Major Market:
Durham

Nearest Secondary Market:
Raleigh