Assistant Research Practice Manager

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe.

Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

At Duke, we celebrate individuality and the unique perspectives that each member of our community brings. As the Assistant Research Practice Manager, you’ll be a vital part of a collaborative, interdisciplinary research environment where you support clinical research professionals and investigators across diverse therapeutic areas. Your leadership will help ensure that excellence, learning, and innovation continue to thrive in our Clinical Research Units (CRUs).

As the Assistant Research Practice Manager, you’ll help shape the research experience at Duke by driving high‑quality study conduct, supporting staff development, and strengthening research operations. Your work will directly influence clinical research quality, compliance, and team success.

• Participate in screening, interviewing, and hiring CRPs in collaboration with faculty and the RPM.
• Support onboarding, training, and advancement of CRPs in partnership with DOCR and SOM resources.
• Manage staff study assignments and effort distribution based on volume and competency.
• Conduct performance evaluations and improvement plans as needed.
• Oversee CRU study operations including initiation, recruitment, enrollment monitoring, and close‑out.
• Provide study metrics and operational updates to the RPM.
• Partner with the RPM to enhance CRU processes, policies, and efficiency.

• Supervise study conduct, ensuring compliance with GCP, institutional standards, and regulatory requirements.
• Oversee screening, recruitment, retention, study visits, documentation, monitoring, and audit readiness.
• Support development of corrective action plans following internal or external audits.
• Guide teams in developing recruitment strategies and addressing enrollment barriers.
• Lead multidisciplinary research meetings and ensure follow‑up on action items.
• Assist with IDS/ICS coordination and international regulatory documentation when required.

• Ensure proper submission and documentation for IRB activities, consent processes, safety reporting, and AE documentation.
• Provide expertise on ethical study conduct and regulatory expectations.

• Oversee data workflows, quality assurance, data security, and compliance with institutional data policies.
• Perform data audits and implement corrective actions when needed.
• Guide teams in implementing new data capture technologies.
• Support CRU teams with data‑related planning, reporting, and return‑of‑results activities.

• Assist with documentation of scientific review processes.
• Support budgeting and negotiation efforts with study sponsors.
• Serve as a primary contact during study startup and help resolve conflicts with sponsors or CROs.
• Collaborate with CRU Financial Practice Manager and RPM on study feasibility and selection.
• Provide operational oversight to ensure protocol adherence and financial milestone tracking.

• Promote participation in DOCR career development programs.
• Keep teams updated on new regulations and institutional policies.
• Represent the CRU and Duke in…