IT Help Desk Specialist
Listed on 2026-07-28
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IT/Tech
IT Support, Systems Administrator, HelpDesk/Support, Technical Support
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit
GRAIL is seeking an IT Help Desk Support Specialist to deliver exceptional technical support that enables our employees to do their best work every day. As a member of the IT End User Services team, you ll support a Mac-first environment while helping maintain the reliable, secure technology that powers our mission to detect cancer early.
In this role, you ll troubleshoot a wide range of hardware, software, identity, networking, and collaboration technology issues while supporting employees across the organization. You ll also help improve IT operations by contributing to documentation, process improvements, technology deployments, and a high-quality employee support experience.
This is an onsite role based in Durham NC at our state of the art lab. Occasional evening, weekend, or on-call support may be required to support system maintenance, technology deployments, or business-critical incidents. GRAIL currently runs two shifts and is moving to 24x7 in the fall. On call will rotate.
Responsibilities- Serve as the primary point of contact for employee technical support, resolving hardware, software, identity, and connectivity issues with a strong focus on customer experience.
- Troubleshoot and support Mac computers, ChromeOS devices, Google Workspace, Microsoft 365, Slack, Zoom, Zoom Rooms, printers, mobile devices, and enterprise SaaS applications.
- Diagnose and resolve network connectivity issues involving Wi-Fi, VPN (Global Protect/Prisma), DNS, TCP/IP, and remote access technologies.
- Perform device imaging, deployment, configuration, refresh, repairs, and lifecycle management using Jamf and enterprise device management tools.
- Support employee onboarding, transfers, and offboarding by provisioning hardware, user accounts, system access, and identity management through Okta and multi-factor authentication.
- Maintain accurate IT asset inventory and equipment records while ensuring compliance with audit requirements and regulated operating procedures.
- Escalate complex technical issues to specialized IT teams while maintaining ownership of incidents through resolution and providing timely communication to end users.
- Support conference room technology, executive users, and collaboration tools to ensure reliable meeting experiences.
- Create and maintain knowledge base articles, troubleshooting documentation, and standard operating procedures to improve team efficiency and enable employee self-service.
- Identify recurring issues, recommend process improvements, and participate in technology rollouts, endpoint management initiatives, and other IT projects.
These responsibilities summarize the role s primary responsibilities and are not an exhaustive list. They may change at the company s discretion.
Required Qualifications
- Bachelor s degree or equivalent experience.
- 3-5 years of IT Help Desk or Desktop Support experience.
- Proficiency in MacOS, Chrome operating systems
- Proficiency in enterprise productivity platforms Google Workspace and O365.
- Proficiency in Slack, Zoom, Zoom Room and AV setup activities.
- Good understanding of networking concepts (TCP/IP, DNS, VPN, Wi-Fi) and enterprise IT security practices. Global Protect/Prisma VPN.
- Understanding of identity management and MFA.
- Familiarity with enterprise SaaS applications.
- Strong troubleshooting,…
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