Data Engineer , Operational Technology - Operations

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

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As a Data Engineer on the Operational Technology team, you will build and maintain the data pipelines that connect GRAIL's lab instruments, automation systems, and operational platforms to a trusted, well modeled data foundation. You will own well scoped ingestion and transformation pipelines end to end, partnering with systems engineers, lab operations, data scientists, and automation engineers to keep data flowing reliably from the lab floor to the analytics and AI systems that depend on it.

This is a hands‑on role for an engineer who is ready to take ownership of real data infrastructure and grow quickly in a fast paced, regulated environment. Expect to work alongside a talented and highly motivated team that moves quickly.

This role is based on‑site in RTP, North Carolina, Monday through Friday. The position participates in an on‑call rotation and may occasionally require weekend or holiday support for production incidents, maintenance, or critical deployments.

• Build and maintain data pipelines that ingest and integrate information from laboratory instruments, automation systems, sequencers, operational platforms, APIs, autonomous robotics platforms, databases and file based data sources.

• Support downstream analytics, reporting, and AI systems by delivering clean, trustworthy datasets and timely data extracts for troubleshooting, root‑cause investigations and platform improvements.

• Develop and optimize SQL and transformation logic to cleanse, standardize, and model raw instrument and production data into reliable, well structured datasets.

• Build and support datasets and data models used by operational dashboards, analytics, process monitoring, troubleshooting, and governed AI enabled workflows.

• Implement orchestration, testing, monitoring and alerting so that data failures, freshness issues, schema changes, and incomplete processing are identified early.

• Implement data validation and quality checks to ensure datasets are accurate, complete, and reliable.

• Document pipelines, data models, and datasets to support reproducibility and compliance with ISO, CLIA, CAP, NYS, GMP, and FDA requirements.

• Continuously improve your technical skills and the team's engineering practices.

• Degree in Computer Science, Mathematics, Software Engineering, Data Science, Life Sciences, Physics or similar field.

• 1+ years of relevant professional, internship, academic, or project experience in data engineering, analytics engineering, software development, or a related field, or equivalent practical experience.

• Proficiency in SQL.

• Working proficiency with one or more programming languages, such as Python, Rust, C++, or similar.

• Basic understanding of ETL or ELT pipelines, relational databases, and structured or semi‑structured data.

• Strong attention to detail and a commitment to data quality, reliability and accuracy.

• Ability to collaborate effectively in teams of technical and non‑technical individuals, and comfortable working in a rapidly changing environment with dynamic objectives and fast iteration.

• Ability to investigate technical problems methodically, continuously learn and communicate clearly.

• A highly analytical mindset and eagerness to solve technical problems.

• Familiarity with data…