Supply Chain Planning Manager

Location and Work Arrangement

Durham, North Carolina – this role is based at our Durham office and offers a flexible working arrangement. You may work from the GRAIL office or from home, with a minimum of 60% (24 hours) of the work week on-site. Your schedule will be determined in collaboration with your manager based on team and business needs.

• Conduct advanced demand and inventory analysis to develop replenishment strategies, optimize working capital, and reduce risk of supply disruptions.
• Manage specific inventory items from end‑to‑end planning, acquisition, inventory receipt, material transfer approvals, and work orders.
• Analyze demand forecasts, historical usage, and system variances; identify risks and develop recommendations for optimal material availability.
• Maintain Bill of Materials (BOM) records in MRP software platforms for vertically integrated material relationships.
• Develop and deliver supply chain performance reports and dashboards, providing insights and recommendations to management for strategic decision making.
• Lead project‑based work throughout the year (e.g., S&OP process owner, safety stock process owner, ERP process owner).
• Act as a subject‑matter expert on planning and supply chain processes and systems, advising internal stakeholders on best practices and solutions.
• Lead resolution of significant material issues, escalating when necessary to ensure minimal business disruption.
• Partner with cross‑functional teams on process optimization, supply chain automation initiatives, cost savings, and operational improvements.
• Mentor and provide guidance to junior specialists and coordinators, sharing knowledge and expertise to build team capability.
• Ensure compliance with company policies, industry standards, and applicable regulatory requirements.

• Taking on additional responsibilities.
• Participating in cross‑functional projects and initiatives.
• Adapting to new technologies, processes, or methodologies.
• Supporting other departments or teams during periods of high demand.
• Contributing to special projects or temporary assignments as needed.

• Bachelor’s degree in Supply Chain Management, Business Administration, Operations Management, or a related field; or a Master’s degree in a related field.
• 6+ years of relevant work experience in supply chain, procurement, logistics, or a related function; or a Master’s degree with 3+ years of relevant experience; or a PhD with 2+ years of relevant experience.
• Advanced proficiency in ERP and supply chain management systems, and strong knowledge of reporting and analytics tools.
• Demonstrated knowledge of applicable regulatory standards commensurate with the position’s complexity and scope, contributing to organizational regulatory compliance.
• Occasional travel may be required for supplier meetings, site visits, or project execution.

• 8+ years of relevant work experience in supply chain, procurement, logistics, or a related function; or a Master’s degree with 5+ years of relevant experience; or a PhD with 2+ years of relevant experience.
• Minimal applicable standards for this position include:
  • GMP quality management systems (e.g. ISO 13485)
  • Clinical laboratory regulations (e.g. CAP, CLIA, NYSDOH, ISO 15189)
  • Operations within the regulated medical device environment (e.g. IVDD, IVDR, FDA 21 CFR 800 series, FDA 21 CFR Part 11)
• Advanced background in MRP and Excel‑based material modeling solutions, including scripting languages for customized solutions.
• Strong analytical and problem‑solving skills for complex planning challenges.
• Proven ability to lead cross‑functional initiatives and drive measurable process improvements.
• Advanced organizational and prioritization skills to manage competing priorities in a dynamic environment.
• Leadership ability to mentor junior staff and serve as a resource for the broader team.
• High attention to detail; organized with the ability to track many activities simultaneously.
• Excellent written and verbal communication skills; strong ability to influence internal stakeholders.
• Thrives in a dynamic environment; team player and collaborative peer.