Director, Supply Chain Planning

Company Overview

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double‑stranded breaks in the DNA.

This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values‑driven organization committed to its people, cutting‑edge science, and a vision of providing life‑long cures to patients suffering from serious diseases.

The Global Supply Chain Planning & Network Strategy leader will be responsible for the supply and raw material planning function, supply network design and optimization strategy, inventory ownership and ensuring a strong supply and raw materials plan handoff to internal and external partners. He/she will be accountable to ensure uninterrupted supply of clinical and future commercial products via Beam’s Clinical S&OP process.

This role will report to the VP of Supply Chain and partner with leadership in Tech Ops, Clin Ops, Finance, CMC and Program Teams to lead short‑term integrated production and raw materials planning and long‑range strategic supply chain planning of Beam’s product portfolio. This role will partner with Patient Supply to secure clinical supply needs and with Commercial, CMC, Engineering and PD for commercial supply chain design and capabilities of late‑stage clinical development programs.

This role will be accountable for designing and implementing core capabilities that drive proactive modeling and decision analysis of supply network and product strategy including governance, S&OP business processes and technology to support this work. The role will be responsible for developing and executing a global inventory management program to ensure raw and critical material availability at Beam NC & CDMO mfg sites.

The role will be integral to enhancing site planning and scheduling capabilities at Beam’s mfg site in Durham, NC and partnering with SAP business lead on further advancing technology capabilities.

The ideal candidate will have a demonstrated track record of leading in a dynamic environment. They will also possess the ability to successfully interface with multidisciplinary teams and build strong cross‑functional relationships.

• Develop and implement supply chain analytics, planning, and resilience processes and policy across the global supply chain for all stages of the product lifecycle.
• Oversee and manage global end to end supply planning and network design as Beam transitions from clinical to commercial stage company over next few years.
• Ensures appropriate inventory, including design/policy for Raw and Critical Materials (pDNA, mRNA, gRNA, mAb, lipids), Drug Substance, Bulk Drug Product, and Finished Drug Product.
• Oversee and manage S&OP process. Collaborate cross‑functionally with Clin Ops and Program teams to ensure accurate demand forecasts and scenarios/analytics. Responsible for supply network analysis to support tactical and strategic decision making.
• Coordinate with Finance, Program Teams, CMC and PD to ensure robust modeling of product and network scenarios to support decision‑making in governance forums.
• Perform risk‑based review of supply chain in order to determine appropriate inventory levels. Communicate demand uncertainties or risks and develop options for optimizing supply network capacity and capabilities.
• Deliver a response plan for disruptive challenges.
• Ensure that plan and capabilities of each CDMO and suppliers are adapted to minimize the risk of disruption and deliver an effective response to ensure resilience.
• Ensure optimal economics, and adequate supply chain security in partnership with Finance for Budget, LRP and capital planning processes.
• Oversee…