Senior MES Engineer; Pharma

We are looking for a talented Senior MES Engineer (Pharma) to support and enhance Manufacturing Execution Systems used in regulated pharmaceutical manufacturing environments.

We are a global life sciences manufacturing organization focused on modernizing and expanding paperless manufacturing operations through enterprise MES platforms.

• Work Location: Hybrid onsite in Durham, NC (4 days per week)
• Employment Type: Contract-to-Hire
• Rate Range: $60–$70/hr W2

This role is NOT eligible for visa sponsorship or C2C

• Support and maintain PMX or Plex or Factory Talk Pharma Suite MES systems in GMP manufacturing operations
• Troubleshoot MES issues and act as a Tier 2 escalation point for production support
• Assist with MES deployments, upgrades, and functional enhancements across manufacturing sites
• Develop, configure, and support Electronic Batch Records (EBRs) and Master Batch Records (MBRs)
• Partner with engineering, manufacturing, IT, and quality teams to deliver compliant MES solutions
• Maintain validation documentation throughout the system lifecycle (CSV)
• Contribute to MES standardization and site‑to‑site replication initiatives

• 5+ years of experience supporting Manufacturing Execution Systems (MES) within pharmaceutical manufacturing industry.
• Experience with Recipe Authoring for PFS (prefilled syringe) or similar Parenteral pharmaceuticals
• Hands‑on experience with PMX or Plex or Factory Talk Pharma Suite in a pharmaceutical manufacturing environment (or other MES platforms such as:
  Siemens Opcenter, SAP Digital Manufacturing, No
  
  Muda Visual Factory, Infor MES, Tulip Platform, iBase-t Solumina MES, Oracle Cloud Manufacturing, Dassault Systems DELMIA Apriso, DELMIAWORKS, HYDRA X, GE Vernova Proficy Smart Factory, L2L (Leading2
  
  Lean), Werum PAS-X MES Suite by Korber Pharma, iTAC.MOM.Suite by iTAC Software, Pro Manage, TrakSYS by Parsec, 42Q, AVEVA Manufacturing Execution System, Trackwise by Honeywell, Honeywell Forge Operations Management, PINpoint MES, Emerson Syncade,Master Control Manufacturing Excellence, Aegis Software Factory Logix, Epicor Advanced MES, Sepasoft MES, ABB Ability Manufacturing Operations Management Suite, Tempo Manufacturing Cloud, Aptean Process Manufacturing OEE, Accevo MES, DeltaV Manufacturing Execution System by Emerson, AspenONE MES, Nexplant MESplus, Cantier MES, or Vimachem Pharma MES)
• Familiarity with GAMP 5, 21 CFR Part 11, and Annex 11
• Working knowledge of GMP, CSV, and regulated systems
• Bachelor’s degree in Engineering, Computer Science, IT, or equivalent experience

• Contract‑to‑hire opportunity with long‑term career potential
• Hands‑on role supporting critical pharmaceutical manufacturing systems
• Exposure to enterprise MES modernization and Pharma Suite transformation initiatives
• Collaborative, cross‑functional environment with engineering, IT, and quality teams
• Competitive hourly rate and on‑call rotation compensation

Manpower Group is committed to providing equal employment opportunities in a professional, high quality work environment. It is the policy of Manpower Group and all of its subsidiaries to recruit, train, promote, transfer, pay and take all employment actions without regard to an employee's race, color, national origin, ancestry, sex, sexual orientation, gender identity, genetic information, religion, age, disability, protected veteran status, or any other basis protected by applicable law.