Bioinformatics Scientist

** Job Family**  **:*
* Scientific Research & Analysis

** Travel Required**  **:*
* None

** Clearance Required**  **:*
* Ability to Obtain Public Trust

** What You Will Do**  **:*
* We are currently searching for Bioinformatics Scientist to provide bioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis.  This is a full-time, on-site opportunity in Durham, NC.

+ Collaborate with scientists to design, analyze, manage and interpret all types of data.

+ Conduct analyses on Next Gen sequencing data including data derived in ChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models.

+ Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries.

+ Conduct analysis and interpretation on data from genomic platforms including expression, exon, tiling, promoter and others array types.

+ Work independently with research groups to develop, implement, and refine analytical pipeline for single cell data analysis.

+ Develop, optimize, and maintain bioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS, scRNA-seq, multi-omics).

+ Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights.

+ Collaborate with scientists and researchers to design experiments, select appropriate analytical approaches, and troubleshoot methodologies.

+ Integrate and analyze diverse genomic and multi-omic datasets, including sequencing and public data sources.

+ Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation.

+ Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences.

+ Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs.

+ Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques.

+ Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications.

+ Support interdisciplinary collaborations and contribute to advancing research objectives aligned with organizational mission.

+ Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

** What You Will Need**  **:*
* + Master's degree in bioinformatics, biostatistics, computational biology or biological/life science.

+ At least TWO (2) years of data analysis experience.

+ Advanced proficiency in disciplines such as statistical modeling, machine learning, and integrative analysis to extract biologically meaningful insights from complex cellular systems.

+ Knowledgeable with a variety of next gen sequencing techniques.

+ Experience working with analytical tools, software and platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat / Scanpy, Linux, Unix, Bioconductor, Cloud computing, High-Performance Computing (HPC).

+ Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred

** What Would Be Nice To Have**  **:*
* + PhD preferred

+ Strong verbal and written communication skills

+ Familiar with multiple next gen sequencing techniques

+ Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions.

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* What We Offer:

*
* Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

+ Medical, Rx, Dental & Vision Insurance

+ Personal and Family Sick Time & Company Paid Holidays

+ Parental Leave

+ 401(k) Retirement Plan

+ Group Term Life and Travel Assistance

+ Voluntary Life and AD&D Insurance

+ Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

+ Transit and Parking Commuter Benefits

+ Short-Term & Long-Term Disability

+ Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

+ Employee Referral Program

+ Corporate Sponsored Events & Community Outreach

+  annual membership

+ Employee Assistance Program

+ Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and  protection, etc.)

+ Position may be eligible for a discretionary variable incentive bonus

** About Guidehouse*
* Guidehouse is an Equal Opportunity Employer-Protected Veterans,…