Research Associate II, Delivery

## Research Associate II, Delivery Apply remote type:
Onsite locations:
Durham, NCtime type:
Full time posted on:
Posted 30+ Days Agojob requisition :
R26-90

Ask Bio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease.

Ask Bio’s gene therapy platform includes Pro
10TM, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.
** Our vision:
** Pioneering science to create transformative molecular medicines.
** Our mission:
** Lead innovative science and drive clinical outcomes to transform people's lives.
** Our principles:
*** Advance innovative science by pushing boundaries.
* Bring transformative therapeutics to patients in need.
* Provide an environment for employees to reach their fullest potential.
** Our values:
*** Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
* Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
* Embrace Responsibility. We are humbled by the enormity of our mission.  We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
* Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
* Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
** Position Summary
** Ask Bio is seeking a motivated, detail-oriented, and collaborative Research Associate II to support AAV delivery research within the Delivery organization in R&D. This role provides hands-on experimental support across molecular biology and cell-based workflows that advance Ask Bio’s preclinical gene therapy pipeline. The Research Associate II will work closely with scientists within the Delivery team to execute established experimental protocols with increasing independence, generate high-quality and reproducible data, and support day-to-day laboratory operations.

This position is based in Morrisville, North Carolina.
** Job Responsibilities
*** Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR, qPCR, ddPCR)
* Conduct routine mammalian cell culture activities, including maintenance of adherent cell lines and execution of cell-based assays following established SOPs
* Perform in vitro assays including transfection and AAV transduction
* Support in vitro and in vivo studies through sample preparation, tissue processing, and downstream molecular analyses
* Accurately document experimental procedures and results in an electronic laboratory notebook in accordance with data integrity standards
* Analyze data, summarize results, and communicate findings through internal reports or presentations
* Maintain laboratory organization, including reagent preparation, inventory management, and inspection readiness
* Contribute to continuous improvement of laboratory workflows by following SOPs and escalating issues appropriately
** Minimum Requirements
*** Bachelor’s degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field with 2+ years of relevant laboratory experience; OR a Master’s degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field
* Hands-on experience with…