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Bioinformatics Scientist with Security Clearance

Job in Durham, Durham County, North Carolina, 27701, USA
Listing for: Guidehouse
Full Time position
Listed on 2026-08-08
Job specializations:
  • Research/Development
    Data Scientist, Research Scientist, Biotech Research, Biomedical Science
Job Description & How to Apply Below
Job Family :
Scientist Travel Required :
None Clearance Required :
Ability to Obtain Public Trust

What You Will Do:

We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible. Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.

* Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.

* Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/meta genome integration, and biological discovery.

* Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.

* Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.

* Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.

* Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.

What You Will Need:

* Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.

* Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.

* Hands-on background analyzing next-generation sequencing data and genomic datasets.

* Working knowledge of Genome-Wide Association Studies (GWAS).

* Background performing bulk RNA sequencing analysis.

* Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.

* Ability to work with large and complex biological datasets.

* Proven ability to develop bioinformatics pipelines and analytical workflows.

* Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.

* Demonstrated ability to collaborate with multidisciplinary scientific teams.

* Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.

* Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred. What Would Be Nice To Have:
* Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.

* Background supporting federal biomedical or environmental health research programs.

* Strong written and verbal communication skills, including presentation experience.

* Ability to develop custom bioinformatics applications and advanced computational algorithms.

* Familiarity supporting high-performance computing environments.

* Ability to provide bioinformatics training, mentoring, and instructional support.

* Demonstrated contributions to scientific manuscripts and peer-reviewed publications.

* Collaboration across interdisciplinary genomic,…
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