TALENT Pipeline-Principal Scientist; Process Chemistry

Cambrex

Location:

US-NC-Durham

Job :  | Type:
Regular Full-Time | # of Openings: 1 | Category:
Process Chemistry | Cambrex - Durham

• Design and carry out multistep organic syntheses, isolation, and purification of targeted products.
• Must possess a strong understanding of modern organic synthesis methodologies.
• Must have a thorough understanding of modern analytical and spectroscopic techniques and be able to interpret the corresponding data and spectra.
• Ability to conduct literature searches for specific target compounds and use the literature to base a design of alternate routes to these compounds, requiring ongoing professional development to keep abreast of current scientific literature and to discuss these findings with colleagues.
• Must demonstrate a proficiency to carry out laboratory syntheses and purification techniques on scales ranging from milligrams to several kilograms, and design and implement process modifications.
• Requires excellent time management with the ability to manage projects on-time without supervision.
• Ability to author and review comprehensive reports at the conclusion of projects for internal and customer use.
• Work closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Work to ensure that a spirit of teamwork and cooperation always exists within the group.
• Conduct laboratory operations in a safe manner, maintain familiarity with the company's chemical hygiene plan, and exhibit safety awareness and safe work practices.
• Follow responsible actions regarding chemical disposal and maintain compliance with all regulations at the federal, state, and local levels.
• Must demonstrate effective communication skills (both interpersonal and presentations).
• Participate in project team meetings with customers.
• Work closely with manufacturing and GMP operations to coordinate project related equipment and activities.
• Maintain a clean, safe laboratory work area.

Position is directed toward optimization of existing chemical routes and development of alternate chemistry toward key synthetic intermediates and APIs.

Carries out multistep chemical synthesis and product isolation/purification operations in the laboratory, independently or as part of an integrated team.

Chemist utilizes modern analytical tools to determine identity and purity of products made during projects.

Communicates with clients in regular team meetings; prepares R&D reports at the conclusion of projects.

Organic Chemistry Knowledge:
Beginning to demonstrate an understanding of advanced theories in Organic Chemistry/Process Development.

Cross Discipline Knowledge:
Higher level of understanding of the principles of cross-functional departments, including analytical chemistry and engineering.

GMP/Regulatory Knowledge:
Demonstrated understanding of industrial GMP and practical application to Cambrex programs; some ability to provide feedback to clients regarding clinical strategy.

Instrumentation:
Advanced knowledge of HPLC, GC, MS, automated reactor platforms, in-situ reaction monitoring, and ability to train and troubleshoot problems with equipment (and help others).

Communication:
Good written and oral communication skills, ability to communicate with clients without manager supervision.

Problem Solving:
Strong demonstration of problem solving, ability to lead investigations.

Time Management:
Able to maintain timeline of key activities and use time efficiently; ability to handle projects without supervision, though requires regular check-in with manager.

Leadership:
Demonstrated record of mentorship and development of peers, partner lines and ability to support initiatives within the department.

Technical Documentation and Review:
Ability to author and review key technical documents with minimal RFT errors; can write new SOP with manager assistance, keep current lab notebook while practicing GDP.

External Influence:
Ability to lead local project teams and steer clients to desired outcomes; ability to work with management to develop key local laboratory-based initiatives.

Industry…