Clinical Research Nurse Coordinator - Duke Cancer Institute

Clinical Research Nurse Coordinator – Duke Cancer Institute

Work Arrangement:
Hybrid (On‑Site and Remote mix)

Requisition Number: 269193

Regular or Temporary:
Regular

Location:

Durham, NC, US, 27710

Date:
May 22, 2026

You will provide leadership and coordination for multiple, complex oncology clinical trials—including investigational products (IP)—within the Duke Cancer Institute’s Bone Marrow Transplant, Hematology Malignancies & Cellular Therapy Clinical Research Program [BMT]. You’ll collaborate with the Oncology Clinical Research Unit (CRU), Principal Investigators (PIs), sponsors, and study teams to ensure feasibility, compliance, and participant‑centered care. Daily, you will recruit and consent participants, conduct study visits, maintain regulatory documentation, and troubleshoot challenges to keep studies on track.

Your work spans operations, site management, communication, data integrity, leadership, and ethics. If you thrive in complex neuro‑oncology research, enjoy mentoring others, and want to advance breakthrough therapies for brain tumor patients, this role is for you.

• Education:
  
  Graduation from an accredited BSN or Associate Degree in Nursing or Nursing Diploma program. Registered nurses without a BSN must enroll within two years and complete within seven years of start date.
• Licensure/
  
  Certifications:
  
  Current or compact RN licensure in North Carolina; BLS required; maintain active NCBON status and hospital/unit competencies.
• Experience:
  
  Minimum of 12 months of appropriate clinical nursing experience.

• Oncology and/or clinical research experience.
• Familiarity with EDC systems, investigational product handling, and Good Clinical Practice (GCP).
• Experience coordinating multi‑stakeholder studies and supporting site initiation/closeout.

• On‑call:
  Overnight and/or weekend call for Convection‑Enhanced Delivery (CED) infusions.
• Clinical competencies:
  Ambulatory medication administration, medication education and management, adult chemotherapy administration, basic dysrhythmia review, lab result review, adverse event assessment, and patient education.
• Ability to interact effectively with multidisciplinary teams and support patient compliance.
• Compliance:
  Maintain Duke and project‑specific training and certification requirements; follow SOPs, regulations, and protocol requirements governing clinical research.

• Direct study operations for multiple complex neuro‑oncology trials, including feasibility assessments, recruitment and retention strategies, informed consent, scheduling, and execution of participant visits.
• Coordinate site management activities (initiation through closeout), maintain regulatory binders and study‑level documentation, manage delegation of authority logs, record and report adverse events (AEs), and ensure compliance with institutional policies and SOPs.
• Serve as the primary liaison among sponsors, PIs, CRU, monitors, and study personnel; communicate clearly and elevate issues to drive timely resolution.
• Ensure high‑quality data capture in EDC systems; recognize and troubleshoot data issues; uphold data security and provenance standards and support query resolution.
• Partner with finance teams on study payments, participant care expense workflows, and budget development; monitor financial milestones and assist with study budget closeouts.
• Provide RN‑level clinical support aligned with protocol (e.g., ambulatory medication administration, adult chemotherapy administration, adverse event assessment, laboratory review, patient education, and CED infusion call coverage).
• Lead and mentor colleagues; actively participate in team meetings, committees, task forces, and ad hoc groups; contribute to scientific presentations and publications.
• Model research ethics: clearly communicate the distinction between clinical care and research activities to staff and participants; summarize and clarify applicable professional guidelines and codes of ethics.

Join a mission‑driven team within the Duke Cancer Institute’s Bone Marrow Transplant, Hematology Malignancies & Cellular Therapy Clinical Research Program, where discovery, collaboration,…