Postdoctoral Associate

Postdoctoral Associate

Work Arrangement:
On-Site

Requisition Number: 271587 Regular or Temporary:
Regular

Location:

Durham, NC, US, 27710 Personnel Area: MEDICAL CENTER

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe.

Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

The Duke University laboratory of Dorothy Sipkins, M.D., Ph.D. is seeking a highly motivated postdoctoral associate with research interest in metastasis and the tumor microenvironment. Our group has a diverse and stimulating environment with projects in basic and translational research as well as clinical trial studies.

Research:
Dissect the key signaling events that regulate tumor cell peripheral nerve invasion (PNI) in pancreatic cancer. This will include studying the role of integrin alpha-6:laminin and neurotrophin cell signaling interactions in this process. Test the efficacy of integrin alpha-6 blockade to prevent PNI and reduce tumor progression in pancreatic cancer. Analyze primary patient correlative research samples for expression of relevant signaling molecules and their association with PNI and pancreatic cancer disease progression.

Duke University is an exceptional environment for research because of its rich intellectual community and pervasive spirit of collegiality. Duke consists of 10 schools, with 6,484 undergraduate and 8,107 graduate or professional students. The resources and support for postdoctoral fellows at Duke are outstanding, with numerous professional development workshops and training opportunities.

The Sipkins Lab is within the Division of Hematologic Malignancies and Cellular Therapy, a division of the Department of Medicine and part of the Duke Cancer Institute (DCI). The DCI is a single entity that integrates and aligns research and patient care with the goals of decreasing the burden of cancer and accelerating scientific progress.

This position requires a PhD in cell biology, immunology, or other relevant areas of biomedical sciences. Experience in one or more of the following areas is desirable:
1) In vivo mouse models (willingness to work with animal models is a must),
2) Immunology (flow cytometry)
3) Molecular biology techniques. The ideal candidate should be motivated, innovative, with strong problem-solving and interpersonal skills and excitement to learn new techniques.

To apply , please provide CV/biosketch, brief statement of research interests/experience, and contact information for 2-3 references. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging.

Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of our community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical

Job Functions:

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.