Software Engineer — System Integration

Hardware-first Role

This is a hardware-first role: if your experience is primarily in AI/ML, full-stack, or pure software development, we encourage you to carefully consider whether your background aligns before applying.

High-throughput optical microscopy is transforming the science of modern biology — from genetics to drug discovery to synthetic biology. It is rapidly improving efficiency and opening up new possibilities across a wide range of applications.

But scientists today are fundamentally constrained by the limited perspective of traditional microscopes. As field-of-view increases, resolution decreases. Yet modern biology requires an ability to capture precise data across larger areas and at multiple points in time to understand dynamic systems and reduce costs by accelerating tedious workflows.

At Ramona, we've reimagined microscopy for the modern researcher. Our Multi-Camera Array Microscope (MCAM™) is the first of its kind to offer video-speed capture of cellular detail across an entire well plate. By equipping scientists with unprecedented speed, precision, and insight, we're on a mission to advance human health and insight through computational microscopy.

Our foundation is built upon five guiding principles:

• We empower exploration by embracing challenges and nurturing curiosity.
• We pursue understanding to deliver solutions that are transformative and elegantly simple.
• We drive innovation, seeking novel approaches to anticipate the challenges of cutting‑edge research.
• We trust in accountability, maintaining transparency and ownership in all we do.
• We thrive on collaboration, valuing diverse perspectives to achieve shared goals.

Our startup environment is fast‑paced and constantly evolving. Success here is driven by a willingness to embrace new challenges and make a tangible impact on our overall success. Our team members thrive on the edge of innovation, wearing multiple hats and coming up with creative solutions to drive growth. For those who excel in dynamic, ever‑changing environments and are ready to contribute wherever needed, Ramona offers numerous opportunities for professional growth.

However, if you prefer a more structured or predictable work environment, Ramona's fast‑paced environment might not be the best fit. We're looking for team members who are eager to push boundaries and shape the future of microscopy and scientific research.

We are looking for a Software Engineer to own the moment our hardware meets our software — the system integration phase where a microscope goes from a collection of cameras, stages, boards, and optics into a working MCAM ready to ship, and the moments after, when a customer in the field needs help getting the most out of it.

This role lives on the build floor as much as in the codebase. You will work shoulder‑to‑shoulder with our build and manufacturing engineers, writing the Python tooling that brings new microscopes up, debugging the messy problems that only appear when real hardware meets real software, and pushing our instruments to their performance limits on the bench so we know exactly what they can do before they reach a customer.

You will also be the person our customers hear from when something goes wrong in the field — answering remotely most of the time, and traveling on‑site (about 10% of the time) for the trickier hardware/software diagnostics that can only be done in person. We want someone who finds failure modes fast, gets them addressed, and gets instruments shipped with confidence.

Roughly 60% of the work is system integration during builds — bring‑up, characterization, and debugging across the hardware/software boundary. Another 20% is production test and validation of finished microscopes before they leave the building. The final 20% is customer support: helping customers remotely troubleshoot hardware and software issues, and traveling on‑site (approximately 10% of your time) to diagnose and resolve the trickier failures in person.

As builds and field issues reveal gaps in our procedures, you'll author the new SOPs and acceptance criteria that fill them. The problems you'll face haven't been solved before,…