Principal Statistical Programmer

Principal Statistical Programmer

Start Date:

Targeted for mid‑July

We are seeking a Principal Statistical Programmer to provide full end‑to‑end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands‑on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support. The Principal Statistical Programmer will serve as a subject matter expert, ensure high‑quality deliverables, and contribute to programming standards and best practices.

• Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
• Lead and perform development and validation of SDTM datasets
• Lead and perform development and validation of ADaM datasets
• Lead and perform development and validation of Tables, Listings, and Figures (TLFs)
• Ensure all deliverables are compliant with CDISC standards and regulatory requirements
• Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
• Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
• Contribute to and help maintain programming standards, macros, and validation processes
• Review and approve programming deliverables to ensure accuracy, consistency, and quality
• Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
• Proactively identify risks and propose efficient, compliant solutions within timelines

• Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
• Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
• Strong hands‑on experience with SDTM and ADaM dataset development
• Strong hands‑on experience with TLF programming
• Strong hands‑on experience with regulatory submission deliverables
• Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
• In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
• Proven ability to manage complex studies independently from start to finish

The potential base pay range for this role, when annualized, is $98,200.00 - $. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

IQVIA is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law.