Senior Principal Clinical Research Specialist - NV - Irvine, CA; Lafayette, CO or Fridley, MN; Onsite

We anticipate the application window for this opening will close on 19 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first developing innovative medical technologies that improve the lives of 72+ million patients each year.

Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.

The Neurovascular Clinical Research team supports the global clinical development of therapies designed to treat stroke and other neurovascular conditions. This team partners across Clinical, Research & Development, Regulatory, Quality, Health Economics & Reimbursement, Marketing, and Medical Affairs to generate clinical evidence that supports product development, regulatory submissions, and commercialization activities. Primary preference is for candidates based in Fridley/Mounds View, Minnesota;
Irvine, California; or Lafayette, Colorado. This role follows a flexible onsite work model with a minimum of four days per week onsite. Travel requirements are expected to be approximately 25% based on business needs. Check us out on Linked In:
Medtronic Neurovascular

• Lead the planning, execution, and oversight of complex clinical studies and clinical development programs supporting Neurovascular therapies.
• Provide strategic leadership for one or more large clinical studies, ensuring achievement of study objectives, timelines, quality standards, and business priorities.
• Manage multiple studies, work streams, and competing priorities simultaneously in a fast‑paced environment.
• Develop and execute clinical evidence generation strategies that support regulatory, commercial, and product development objectives.
• Partner closely with Clinical, R&D, Regulatory Affairs, Quality, Medical Affairs, Marketing, Health Economics & Reimbursement, and other stakeholders to drive study success.
• Serve as a key liaison with physicians, investigators, external clinical partners, and other stakeholders throughout study execution.
• Present clinical study strategy, progress, risks, and outcomes to senior leaders and executive stakeholders.
• Author and review clinical, scientific, and regulatory documentation, including study protocols, clinical study reports, publications, presentations, and submission support materials.
• Interpret, analyze, and communicate complex clinical data and study outcomes to technical and non‑technical audiences.
• Lead publication and dissemination activities in collaboration with physician investigators, key opinion leaders, and internal stakeholders.
• Monitor emerging scientific literature, competitive developments, and evolving clinical evidence within the neurovascular therapeutic area.

• Bachelor's degree in a technical discipline and 10+ years of relevant clinical research or medical device experience, or an advanced degree with 8+ years of relevant experience.
• Demonstrated experience independently leading complex clinical studies or clinical development programs.
• Proven experience owning study strategy, execution, timelines, stakeholder management, and program outcomes.
• Strong clinical study management expertise within a regulated healthcare, life sciences, or medical device environment.
• Experience interacting with senior leadership and presenting clinical information to executive audiences.
• Exceptional stakeholder management, influencing, organizational, and communication skills.
• Ability to independently drive outcomes and operate effectively in a highly matrixed environment.

• Doctor…