Principal Fluid Systems Engineer - Pharmaceutical Payloads

Principal Fluid Systems Engineer - Pharmaceutical Payloads

El Segundo, California, United States

As a Principal Fluid Systems Engineer on Varda's Payload team, you will define and lead the development of first-of-its-kind electromechanical fluid handling hardware that manufactures pharmaceuticals in microgravity, endures hypersonic reentry, and returns to Earth for material extraction. Your payloads will precisely meter, mix, filter, transport, and thermally control pharmaceutical materials in compact spacecraft-compatible hardware. You'll shape the architecture and technical direction for pharmaceutical payloads—guiding project teams from requirements synthesis through development, on-orbit operation, recovery, and iteration for future missions.

You'll collaborate closely with pharmaceutical scientists, process engineers, internal leadership, and spacecraft subsystem teams to translate mission objectives into qualified hardware that flies in months, not years. This role is ideal for engineers who combine deep mechanical and fluid systems expertise with the cross-functional breadth to define foundational in-space pharmaceutical manufacturing infrastructure.

• Define requirements, architecture, and development plans for pharmaceutical manufacturing payloads
• Establish fluid system design standards for component selection and qualification, sealing, contamination control, thermal control, and verification/validation
• Lead project teams to develop of precision fluid systems incorporating valves, pumps, pistons, manifolds, tubing, fittings, seals, filters, sensors, and thermal control systems
• Drive system-level analyses, trade studies, and risk reduction using a variety of tools (hand calcs, Python/MATLAB models, FEA, etc. as needed)
• Lead build and test campaigns for prototypes and flight hardware to characterize performance and reliability
• Synthesize cross-functional inputs from business development, pharmaceutical science, process engineering, and spacecraft subsystem teams to develop requirements for new pharmaceutical payloads
• Develop standards for subsystem requirements, ICDs, verification plans, test reports, and recovery procedures
• Represent Varda in technical discussions with internal leadership, external partners, customers, and government stakeholders
• Lead continuous improvement and incorporation of lessons learned
• Mentor senior and entry-level engineers and shape best practices

• BS/BEng in Mechanical, Aerospace, Mechatronics, Biomedical, Chemical, or related engineering discipline
• 7+ years of experience designing, integrating, testing, and troubleshooting electromechanical hardware
• Deep mechanical and fluid systems expertise with breadth in at least two adjacent disciplines such as avionics, software, thermal, optics, test, precision instrumentation, etc.
• Track record leading project teams through full-cycle electromechanical space flight hardware development
• Extensive experience with valves, pumps, pistons, tubing, manifolds, fittings, seals, filters, sensors, metering hardware, thermal-control hardware, and/or compact fluidic assemblies
• Excellent communication skills with customer, executive, and cross-disciplinary technical audiences

• 3+ years of cross-functional project leadership experience
• Prior full-cycle technical leadership of precision fluid-handling hardware for relevant applications
  • In Space: ECLSS, low-thrust propulsion, astronaut suits, spacecraft thermal control, etc.
  • On Earth: semiconductor process equipment, biotech process equipment, analytical instruments, medical devices, etc.
• Extensive experience planning and executing aerospace environmental testing (vibration, TVAC, EMI/EMC)
• Familiarity with microgravity fluid behavior, capillary-driven flows, gas/liquid separation, two-phase flow, cGMP principles, cleanroom practices, or regulated hardware environments

• Salary range: $180,000 - $230,000/per year
• This role is on-site in El Segundo, CA
• Leveling and base salary is determined by job-related skills, education level, experience level, and job performance
• You will be eligible for incentives in the form of stock…