Senior Infrastructure and Security Engineer

Attention recruitment agencies:
All agency inquiries are vetted through 4

DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4

DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4

DMT in the future.

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DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company’s lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections.

The Company’s lead indication for 4D-150 is wet age-related macular degeneration, which is currently in Phase 3 development, and second indication is diabetic macular edema. The Company’s second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery.

We areseekinga highly skilled and experienced Senior Infrastructure and Security Engineer to join our dynamic and growing team. This role is pivotal in ensuring the seamless operation, scalability, and security of 4

DMT’s IT infrastructure, enterprise end-user services, and cloud environments. The Senior Infrastructure and Security Engineer will play a key role in designing, implementing, and maintaining cutting-edge infrastructure and security solutions to support organizational growth and innovation.

This role oversees 4

DMT’s

• IT endpoint infrastructure and enterprise end-user services
• IT infrastructure, including servers, cloud services, hardware systems, and applications
• Planning and implementation of comprehensive infrastructure solutions aligned with organizational needs.

Infrastructure Design & Management

• Plan, design, develop, and implement scalable, secure, and user-focused hybrid IT solutions, including world‑class infrastructure, Cloud, high‑end workstations, desktops, laptops, mobile devices (secure BYOD).
• Manage virtualization technologies (e.g., VDI/VM) to enable flexible work arrangements.
• Deploy and configure Windows, macOS, and Linux operating systems to ensure compatibility, performance, and compliance with security standards.
• Administer and support Active Directory environments, including Group Policy management, user accounts, and domain controller maintenance.
• Maintain and optimize Windows Server and Linux systems, ensuring high availability, security, and performance.
• Support Google Cloud Platform (GCP) infrastructure, including compute, storage, and networking services, while leveraging GCP tools for monitoring, security, and cost optimization.
• Implement and maintain system images, software packages, and productivity/business applications.

Automation & Optimization

• Develop and manage automation scripts and workflows to optimize operations, enhance user experience, and increase efficiency.
• Build comprehensive automated infrastructure management solutions, including configuration management, monitoring, and analytics, to improve operational efficiency and reliability.
• Continuously identify opportunities for automation and process improvement, driving innovation and operational excellence.

System Monitoring & Troubleshooting

• Proactively monitor system performance and ensure high availability, reliability, and scalability.
• Rapidly troubleshoot and resolve hardware, software, and system issues, including those related to Active Directory, Windows, Linux, and GCP environments.

Security & Compliance

• Security Operations:
• Implement and maintain cybersecurity controls for infrastructure and endpoints, including vulnerability management and data loss prevention.
• Support the detection and response to security incidents,…