Research Associate, Formulation Development

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DMT in the future. 4

DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company's lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections.

The Company's lead indication for 4D-150 is wet age-related macular degeneration, which is currently in Phase 3 development, and second indication is diabetic macular edema. The Company's second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery.

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DMT is seeking a motivated Research Associate, Formulation Development (Contract) to support pre-formulation and formulation development activities for biologic products. This role reports to the Principal Scientist, Process Development. This contract role requires onsite, lab-based work five days per week in Emeryville, California. Primary responsibilities include formulation screening, accelerated stability, forced degradation, material/device compatibility and formulation analytics. Requisites include a B.S. degree, a willingness to learn, good communication skills and a general enthusiasm for science.

• Execute high-throughput, plate-based formulation screening, including formulation preparation, stability studies, sample testing, data analysis, and documentation.
• Support prefilled-syringe and other container/device compatibility assessments.
• Formulation analytics including but not limited to Size-Exclusion Multi-Angle Light Scattering, Differential Scanning Fluorimetry, Dynamic Light Scattering, pH and osmo testing.
• Collaboration with Upstream PD, Downstream PD and AD/QC.

• Bachelors of Science Degree

• Bachelors of Science Degree

• 0+ years of experience within the Biotech or similar industry
• Strong foundational laboratory skills, including accurate pipetting, solution preparation, weighing, basic laboratory calculations, and data organization using Excel.
• Hands‑on laboratory experience gained through academic research, internships, or industry.
• Experience with preformulation, formulation development, stability studies, drug-product process development, or downstream process development is preferred.
• Experience with biologics, including proteins, antibodies, or AAV/gene therapy, is a plus.

• Applicant should possess a general competency in Microsoft based applications (e.g., Word, Excel, PowerPoint)
• Prior experience with statistical tools (e.g., JMP) or Prefilled Syringe development is preferred, but not required.

Travel:
This role does not require travel outside of the main office. However, may provide opportunities to travel in future (e.g., to attend conferences or oversee outsourced activities).

• Physical Activity
  - Repetitive motions:
  Making substantial movements (motions) of the wrists, hands, and/or fingers. Fingering:
  Picking, pinching, typing or otherwise working, primarily with fingers rather than with whole hand or arm as in handling. Talking:
  Expressing or exchanging ideas by means of the spoken word.
• Physical Requirements
  - Lifting up to 20 lbs, bending, lifting, twisting, ability to wear Personal Protective Equipment such as lab coat, goggles/glasses, and nitrile gloves
• Working Conditions
  - The worker is not substantially exposed to adverse environmental conditions (as in typical office or administrative work).

Hourly compensation range: $39.00 - $45.00 / HOUR

Please note, the base salary compensation range and actual salary offered to the final candidate depends on various factors: candidate’s geographical location, relevant work experience,…