Scientist II, Flow Cytometry

Scientist II, Flow Cytometry (Fixed-Term Contract)

Emeryville, CA

Slingshot Biosciences is a fast-growing life sciences company with a platform technology and paradigm-shifting mission to make precision-engineered cell mimics the gold standard for all cell-based assay controls. We are transforming cell-based applications with the most robust, scalable, and reproducible controls available, including Tru Cytes™ Biomarker controls, Spectra Comp® compensation controls, Via Comp® cell health controls, and Flow Cytes® instrument controls.

Our Tru Cytes cell mimics precisely replicate real cells' optical and biochemical properties - without the sourcing, quality, or cost challenges of traditional controls. Trusted in cell-based applications across cell therapy, drug development, and diagnostics, they empower process and analytical development, quality control, potency assessments, multi-site validations, clinical research studies, and assay development and validation.

Slingshot is seeking motivated, creative team members who think outside the box. We empower employees to own their work, contribute ideas quickly, and improve processes. Come join our cross-disciplinary and world-class team that is delivering game-changing solutions for cell-based applications!

We're looking for a Flow Cytometry Scientist II to join us on a fixed-term contract basis and help us build our next portfolio of products. You'll be a key part of our product development process, partnering closely with R&D and Manufacturing to bring new ideas to life. You'll also generate publication-quality results for competitive marketing and general publication and release, and dig into root cause investigations behind product complaints.

This is a three-month engagement reporting to the technical lead of our Flow Cytometry function.

Location:

100% onsite in Emeryville, CA. This role reports to the technical lead of our Flow Cytometry function. This role requires up to 25% travel.

What You'll Do

• Test, validate, and characterize new product designs using both spectral and conventional flow cytometers across multiple platforms.
• Develop, optimize, and transfer protocols for sample preparation, staining, acquisition, and data analysis to ensure accurate and reproducible results.
• Perform QC testing, analyze flow cytometry data using software such as Flow Jo, and ensure results meet established specifications and acceptance criteria.
• Plan and execute verification/validation and stability studies, including accelerated stability studies, data analysis, and technical reporting.
• Support QMS and design control activities, including controlled documentation, deviations, investigations, CAPA, change control, and design reviews.
• Perform instrument maintenance, calibration, troubleshooting, and performance verification across multiple flow cytometry platforms.
• Investigate product performance issues and complaints and support root cause analysis and corrective actions.
• Develop SOPs and support method transfer from R&D into production.
• Conduct product testing, demonstrations, and technical evaluations at local flow cytometry core facilities and customer/partner sites; travel as needed.
• Maintain compliance with laboratory safety, ISO 9001, GMP, and applicable quality requirements.
• Other duties as assigned.

What You'll Bring

• Strong expertise in multiparameter (>10-color) flow cytometry analysis, compensation and gating strategies for analysis of mixed cell populations.
• Experience analyzing flow cytometry data in software such as Flow Jo.
• Experience with QC testing and QMS processes in a regulated or quality-focused environment.
• Strong understanding of stability principles, including shelf life determination and accelerated stability testing.
• Good knowledge of laboratory health and safety standards, including working with blood products such as Leukopaks.
• Excellent analytical and research skills.
• Attention to detail and excellent communication skills/systems in record keeping and documentation.
• Demonstrated ability to independently lead technical projects and resolve complex scientific problems.
• PhD in Biology, Cell Biology, Biochemistry, Immunology, or a related field with 3+ years…