Principal Scientist - Cancer Vaccines

ICR's Cancer Prevention science is centered on developing prophylactic cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology.

• Lead our Cancer Prevention Group in researching and developing novel preventive cancer vaccines

• A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines
• In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines
• Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring
• Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT
• Experience deriving antigen-specific T cell clones and lines
• Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring
• Extensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systems
• The ability to work well with CROs and manage external projects

• The ability to work in the United States without sponsorship
• To have an easygoing, hard-working personality

Starting base pay range: $165,000/yr - $205,000/yr

Starting additional compensation range: $7,500/yr - $20,000/yr

Starting position title and compensation are commensurate with experience.