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Principal Scientist - Cancer Vaccines

Job in Englewood, Bergen County, New Jersey, 07631, USA
Listing for: BioSpace
Full Time position
Listed on 2026-09-14
Job specializations:
  • IT/Tech
    Data Scientist, AI Engineer (Applied/Software), Data Analyst, Data Science Manager
Salary/Wage Range or Industry Benchmark: 165000 - 215000 USD Yearly USD 165000.00 215000.00 YEAR
Job Description & How to Apply Below

ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure.

With

Us, You’ll Get To
  • Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccines
  • Drive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translation
  • Collaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programs
  • A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines
  • In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines
  • Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring
  • Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT
  • Experience deriving antigen-specific T cell clones and lines
  • Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring
  • Extensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systems
  • The ability to work well with CROs and manage external projects
  • Even if you don't meet all of these criteria, please apply anyway
And You’ll Need
  • The ability to work in the United States without sponsorship
  • To have an easygoing, hard-working personality
Salary

Starting base pay range: $165,000/yr - $215,000/yr

Starting additional compensation range: $7,500/yr - $20,000/yr

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