Senior Data Scientist - Genetics

Senior Data Scientist - Genetics Job Description Summary

The UPenn department of genetics is seeking a Senior Data Scientist for clinical genomic pipeline design and implementation.

The successful candidate will be working with a broad team of quantitative analysts, including Statisticians, Data Scientists, Clinical and Basic trainees, and other bioinformaticians. Their role will involve developing and implementing new quantitative strategies to improve our understanding and ability to diagnose genetic disorders through large‑scale, clinically graded genomic testing. Senior Data Scientists are passionate about applying their knowledge of biology and methods for molecular, cellular or radiologic data‑analysis to uncover general principles of genetic disorders and use these to create clinically useful biomarkers.

They will develop, extend and apply computational pipelines for data analysis to patient cohorts ranging from tens of individuals to hundreds of thousands. These will be executed at scale via distributed software solutions on both local HPC and cloud‑based assets. Our datasets comprise petabytes and are growing rapidly, linked to key clinical endpoints. This requires a strong background in biology to help ensure the right questions are asked, but also linked to strong technical and personal communication skills to help ensure insights are broadly adopted and appropriate analyses are performed.

They may work with molecular (WGS, panel‑sequencing, RNA‑Seq, proteomic) or imaging (digital pathology, radiomic) data, and practical experience in one of these two areas is essential. Beyond strong interpersonal skills and a computer science background, you will have experience with implementation skills in at least one of R, Perl or Python. You will be comfortable in UNIX/Linux environments and producing well‑documented code.

Multi‑year experience (>10 years) with cloud‑computing or HPC is essential.

Master of Science and 1 to 2 years of experience, or an equivalent combination of education and experience required. Ph.D. preferred.

This position is contingent upon grant funding.

Philadelphia, Pennsylvania

Perelman School of Medicine

$ - $ Annual Rate

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

• Health, Life, and Flexible Spending Accounts
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• Tuition
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  Take advantage of Penn’s exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here r dependent children are also eligible for tuition assistance at other institutions.

• Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre‑tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.

• Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.

• Long‑Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long‑term care insurance to help you cover some of the costs of long‑term care services…