Senior Principal Analyst; RWA)

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments.

Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit  for more information.

The Senior Principal Real-World Analyst (RWA) will be responsible for conducting analyses for Real-World Evidence (RWE) studies and analytic projects using diverse Real-World Data (RWD) sources including administrative claims, electronic medical records (EMR), and registry data. Reporting to the head of RWD/A, and positioned within the RWE/A, Global Evidence & Value Generation department, the successful candidate will demonstrate deep expertise in RWD analytics, exceptional programming and analytical capabilities, strong organizational skills and a keen eye for detail, and a proven record of delivering high-quality RWE projects.

In addition, the candidate will be responsible for ensuring the timely completion and scientific rigor of all research outputs.

• Conduct and audit RWE analyses using a variety of RWD from multiple sources
• Work collaboratively with the RWA lead and other team members to meet study and recurring report timelines
• Leverage advanced statistical and epidemiological methodologies to deliver robust and reliable results
• Clean and validate RWD and outputs for consistency and reliability
• Maintain clear documentation of analytical programming codes and operational definitions to ensure reproducible and auditable RWE studies/analytic projects
• Develop reports, presentations and dashboards to communicate complex data insights
• Provide support in designing and enforcing RWA standards that improve operational efficiency and guarantee accuracy in RWE studies/analytic projects
• Stay current with evolving RWA methodologies, emerging data visualization technologies, and established industry best practices

• MS or PhD in data science, epidemiology, statistics, public health, or related discipline
• Relevant experience (4+ years for MS, 2+years for PhD) within biopharma companies, RWE consulting firms, or other relevant healthcare industries
• Demonstrated expertise with multiple RWD sources, with extensive hands-on experience working with Flatiron and Optum data (minimum 2 years) required
• Expert proficiency in programming software SQL and R is required. Knowledge of Python would be considered an advantage
• Familiarity with US and global health care coding system (e.g. ICD, CPT, HCPCS, LOINC, MedDRA) and delivery system (e.g. payers and reimbursement models)
• Experience conducting routine and advanced statistical analyses for RWE generation, leveraging time-to-event, cross-sectional, and longitudinal data
• Experience with big data analytical platforms (e.g., Snowflake).
• Knowledge of data visualization tools (e.g., PowerBI) would be considered an advantage
• Relevant experience (4+ years for MS, 2+years for PhD) within biopharma companies, RWE consulting firms, or other relevant healthcare industries
• Highly motivated and intellectually curious, with strong executional rigor and a…