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Scientist II​/III, LCMS Method Development

Job in Exton, Chester County, Pennsylvania, 19341, USA
Listing for: Pharmaron
Full Time position
Listed on 2026-08-15
Job specializations:
  • Research/Development
    Research Scientist, Pharmaceutical Science/ Research, Clinical Research
Salary/Wage Range or Industry Benchmark: 65000 - 85000 USD Yearly USD 65000.00 85000.00 YEAR
Job Description & How to Apply Below

Scientist II/III, LCMS Method Development

Position:
Scientist II/III, LCMS Method Development

Salary Range: $65,000-$85,000

Location:

Exton, PA (On-site)

Pharmaron is seeking a Scientist II/III, LCMS Method Development to join our growing Bioanalytical Sciences team in Exton, PA. In this role, you will contribute to the development and validation of innovative bioanalytical methods supporting drug discovery and development programs across a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, PROTACs, biologics, and emerging therapies.

Key Responsibilities

  • Independently develop, optimize, validate, and troubleshoot LC-MS/MS bioanalytical methods.
  • Design scientifically sound studies that meet sponsor and internal objectives.
  • Execute and support bioanalytical testing for DMPK and regulated studies.
  • Perform sample analysis using HPLC and LC-MS/MS platforms in compliance with developmental and GLP requirements.
  • Review and execute study protocols governing bioanalytical studies and sample analysis.
  • Process, analyze, interpret, and report study data.
  • Author protocols, validation reports, technical summaries, and study reports.
  • Support regulatory submissions through high-quality scientific documentation.
  • Serve as Principal Investigator (PI) and/or Study Director (SD) within areas of expertise.
  • Actively identify and resolve technical challenges while driving continuous improvement.
  • Collaborate with scientists, project teams, management, business development, and clients to ensure successful project execution.
  • Participate in project review meetings and compliance-related initiatives.

What We're Looking For

  • Bachelor's degree in Pharmaceutical Sciences, Chemistry, Life Sciences, or a related scientific discipline.
  • Scientist II:
    Minimum 2 years of bioanalytical testing experience.
  • Scientist III:
    Minimum 4 years of bioanalytical testing experience.
  • Experience supporting development and/or GLP-regulated bioanalytical studies.
  • Strong understanding of HPLC and LC-MS/MS methodologies.
  • Excellent analytical thinking, troubleshooting, and organizational skills.
  • Ability to thrive in a fast-paced, collaborative, and matrixed environment.

Preferred Qualifications

  • Experience with LC-MS/MS method development and validation.
  • Experience analyzing peptides, oligonucleotides, PROTACs, and complex biologics.
  • Familiarity with DMPK studies and regulated bioanalysis.
  • Experience authoring scientific reports and supporting regulatory submissions.
  • Prior CRO, pharmaceutical, or biotechnology industry experience.
  • Experience serving in client-facing scientific roles.

Why Pharmaron?

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the US, UK, China, and Singapore.

Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

Collaborative Culture:
You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values  culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators.

Benefits:
As part of our commitment to your well-being, we offer a comprehensive benefits package:

  • Comprehensive Medical, Dental & Vision Insurance with significant employer contributions
  • 401(k) Retirement Plan with generous employer matching
  • Generous Paid Time Off (PTO), Paid Sick Leave & Company Holidays to support work-life balance
  • Employer-funded Health Savings Account (HSA) contributions (for eligible plans), plus Healthcare & Dependent Care Flexible Spending Accounts
  • 100% Employer-paid Employee Life Insurance, AD&D, Short- and Long-Term Disability Insurance
  • Employee Assistance Program (EAP), mental health resources, and wellness programs
  • Family-friendly benefits, including fertility support and maternity resources
  • Professional development and career growth opportunities within a leading global CRO/CDMO

How to Apply:

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

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