Technical Associate , Yaffe Lab

MIT - Koch Institute for Integrative Cancer Research

Recruitment began on December 22, 2025.

The job listing expires on February 22, 2026.

TECHNICAL ASSOCIATE I,
YAFFE LAB
, Koch Institute for Integrated Cancer Research-Yaffe Lab, to work closely with several lab members and perform independent research using CRISPR-based screens for sensitization of tumor cells to signaling pathway inhibitors and chemotherapeutic drugs, combined with in vivo mouse tumor studies.

• Perform a broad range of basic laboratory experiments using standard techniques, including tissue culture techniques, CRISPR screening, maintaining mouse tumor and human PDX models, delivery of novel anti-cancer therapeutics into mice and target tumors, molecular cloning, immunoblotting, flow cytometry, and other biochemical/molecular assays.
• Conduct statistical data analysis.
• Evaluate, design, and revise research methods/procedures/techniques based on established objectives.
• Adjust basic experimental protocols to ensure project completion in a timely fashion.

• Bachelor’s degree in a relevant field.
• Two years of specialized lab experience (may include experience gained as an undergraduate).
• Working knowledge of general laboratory practices and procedures.
• Experience with mouse cancer models, signal transduction biochemistry, and relevant molecular biology and cell culture techniques.
• Experience conducting and applying online research to projects.
• Excellent communication and interpersonal skills.
• Comfort analyzing, summarizing, and reporting results to researchers.
• Commitment to exceeding quality standards, providing exceptional services, and producing accurate and high‑quality work.
• Meticulous attention to detail.
• Ability to follow safety procedures, maintain a safe work environment, and work independently and as part of a team.

• Master’s degree in related field.
• Broad knowledge of the work done in the labs.
• Experience collaborating with a diverse group of researchers/trainees.

• Exerting light‑to‑medium amount of force to move objects of 10‑20 lbs.
• Moving long distances or from site to site.
• Proximity to mechanical parts and electrical current.
• Exposure to high heat or chemicals.