Senior Quality Scientist

Senior Quality Scientist I

This position will contribute to Addgene’s mission to accelerate research and discovery by improving access to useful research materials and information through ensuring only the highest quality materials are distributed to scientists. The Senior Quality Scientist I will help the Quality team grow Addgene’s catalogue of items available for customers to order while sustaining our high quality of materials offered. Additionally, this position will grow the team’s computational and quality analysis capabilities.

Sr. Manager, Quality

ASAP

$84,000 - 92,000 annually + our amazing benefits! (see below)

This is a hybrid position, with Wednesdays required onsite in our Watertown, Massachusetts Headquarters. Our beautiful office space has free, ample parking with a complimentary shuttle from Harvard Square and is on multiple bus lines, with the cost of public transit covered by Addgene for those onsite at least twice a week.

In this position, you will support Addgene’s mission to deliver only the highest quality materials to scientists around the world. The Senior Quality Scientist I independently owns complex QC analyses and depositor relationships, leads new process development within the QC team, and contributes bioinformatic and scripting expertise to team capability expansion. This role is expected to proactively identify gaps and opportunities within the QC team's existing scope, propose projects, and execute them with minimal direction.

• Independently perform, document, and report quality control (QC) analysis across all sample types and complexity levels, including resolving novel or non-routine QC issues.
  • QC analysis includes verifying sample functionality through DNA sequence analysis of Illumina and Nanopore next generation sequencing data, as well as diagnostic restriction enzyme digests.
• Serve as escalation point for complex depositor communications before escalation up; own end-to-end resolution of difficult cases
• Provide bioinformatic, script writing, and command line expertise to new project development and process optimization plans
• Lead NGS-related bioinformatic processes; serve as a technical resource for post-run data processing, pipeline management, uploading of sequencing results, and troubleshooting.
• Perform additional Quality team duties for specialized sample analyses, internal team processes, and external team communications.
• Contribute to the development of Quality Control team goals and best practices; lead discussions on progress and alignment at team meetings
• Serve as a subject and technical expert on QC tasks, answer team questions, cross-train team members, and update and improve team processes and SOPs.
• Develop and lead new team initiatives to improve quality, efficiency, and scope of performing QC analyses on a variety of samples through different means.
• Author, update, and maintain new SOPs for developmental processes. Cross-train team members on new processes upon launch.
• Occasionally contribute to outreach/marketing initiatives and/or to educational content on our website.

• PhD in Biological Sciences or other life science, MS with 4+ years related experience, or equivalent combination of education and experience.
• Experience with cloning, primer design, and sequence analysis required
• Experience with a programming or scripting language (Python, Bash, R, etc) and command line tools
• Experience with next-generation sequencing analysis using bioinformatic software required
• Working knowledge of standard molecular biology practices including bacterial transformations, DNA preparation, and digests
• Well versed in reading scientific research articles
• Excellent organizational skills and attention to detail
• Able to manage multiple tasks efficiently
• Self-motivated, proactive with desire for continuous improvement
• Mentoring mindset, demonstrating patience and clarity in explanations
• Strong leadership skills with ability to communicate complex information succinctly
• Ability to adapt to changing lab priorities, new technologies, or unforeseen challenges, finding…