Senior Principal Scientist, Translational Clinical Biomarkers

Responsibilities

• Provide strategic and scientific leadership in the design, execution, analysis, and communication of clinical biomarker strategies across the immune‑mediated therapeutic portfolio
• Drive decision‑centric biomarker strategies that connect drug mechanism, disease biology, and precision medicine
• Lead and shape integrated biomarker strategies across discovery, early‑ and late‑stage clinical programs
• Serve as the biomarker strategy lead within cross‑functional program teams
• Inform portfolio strategy by advancing biomarker‑driven insights
• Translate disease biology into clinically actionable biomarker strategies
• Drive selection and application of innovative biomarker approaches
• Collaborate effectively across disciplines to integrate scientific perspectives into cohesive strategies
• Champion biomarker analysis plans and provide critical scientific input to the interpretation of complex datasets

• Ph.D. or M.D. with 12+ years in Immunology or a related scientific discipline
• Deep expertise in immunology and immune‑mediated/inflammatory diseases
• Experience in at least one of the following:
  Gastrointestinal/mucosal inflammation, Rheumatology, Dermatology
• Proven track record of driving translational strategies that inform clinical development decisions
• Strong analytical and problem‑solving capabilities
• Excellent communication skills, including experience presenting to senior leadership
• Working knowledge with biostatistics, bioinformatics, and advanced data analytics
• Strategic mindset with a focus on decision impact rather than data generation alone
• Proven ability to operate effectively in a fast‑moving, matrixed environment