Project Manager II - Veeva Vault Clinical; CTMS & eTMF

Overview

Project Manager II - Veeva Vault Clinical (CTMS & eTMF)

Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress. Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver - for one another, our customers, and, most importantly, for those in need. Discover what your 25,000 future colleagues already know.

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture - where you can authentically be yourself. Central to this is our purpose - Driven to Deliver - which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone's life.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Project Manager II - Veeva Vault Clinical (CTMS & eTMF)

Sponsor-Dedicated | Remote (U.S.)

If you're a Veeva Vault expert who thrives at the intersection of clinical operations, systems, and governance, this is a high-visibility opportunity to take ownership of CTMS and eTMF operations post-go-live within a leading sponsor environment.

This role sits within the Clinical Trial Capabilities Business Support Model, blending hands-on operational ownership (50%) with strategic program support (50%) - ideal for someone who understands both the technical backbone of Vault Clinical and the real-world execution of clinical trials.

Why This Opportunity

• Direct impact on enterprise-wide CTMS & eTMF operations
• High exposure to Clinical Operations, R&D Quality, and IT leadership
• Ownership of post-go-live system governance and optimization
• A chance to operate as a true SME and trusted advisor in a complex, matrixed environment

Operational Ownership & Centralized Support

• Serve as the primary business-facing owner of Vault Clinical in production
• Provide centralized support and guidance to Clinical Operations and key users
• Act as the escalation point for system and process issues, driving resolution across cross-functional teams

Governance, Compliance & Inspection Readiness

• Ensure inspection-ready documentation with strong change control and configuration management
• Support and maintain data governance processes
• Manage and triage change control intake from a business perspective

Change, Release & Lifecycle Management

• Partner with Clinical Systems and IT on impact assessments and controlled changes
• Ensure alignment between system functionality and business processes
• Lead release readiness activities (training, communications, SOP updates)

Stakeholder Partnership & Enablement

• Act as a trusted advisor and SME to stakeholders across Clinical, Quality, and Systems
• Develop and deliver training, job aids, and operational guidance
• Coordinate with vendors and FSP partners, ensuring clear accountability and oversight

Program Support

• Support Program Leads and Business Process Owners (BPOs) through workshops and execution of key initiatives
• Contribute to continuous improvement and optimization efforts across Vault Clinical

• 5+ years supporting GxP-regulated clinical systems, with deep expertise in CTMS and/or eTMF
• Veeva Vault SME - strong understanding of both front-end usage and back-end configuration
• Proven experience in post-go-live system support, governance, and centralized operating models
• Strong (3+ years) project management background in clinical research, including:
• Study oversight, timelines, and deliverables
• Vendor and budget management
• Issue identification and resolution across trial operations
• Experience integrating Veeva Vault within clinical programs
• Demonstrated ability to influence cross-functional stakeholders in a matrixed environment

• Deep understanding of GxP compliance, risk identification, and data integrity
• Ability to translate complex system challenges into practical solutions
• Clear grasp of system governance vs. operational execution
• Confident decision-making with appropriate risk escalation

This is not a passive support role - this is a…