Associate Scientist - Single Cell Biology Lab - Spatial Omics

Associate Scientist - Single Cell Biology Lab - Spatial Omics

10 discovery drive
Single Cell Biology Lab
Farmington , CT 06032
United States

Pay Range: $65,018 - $101,081, pay is determined by experience

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders.
This is a full-time, on site position.

The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab.

Knowledge, Skills, and Abilities

Required

• Education:
  
  Master’s degree (M.S.) in Biology, Molecular Biology, or a related scientific field.
• Experience:
  
  2-4 years of experience in a core facility or industry setting.
• Molecular & RNA Biology:
  Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays.
• Imaging-Based Spatial Genomics Expertise:
  Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seqFISH.
• Technical Breadth:
  Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seqFISH).
• Sample Handling:
  Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques.
• Documentation:
  Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN).
• Operational
  
  Skills:
  
  Proven project and lab management experience, including managing stock, inventory, and instrument uptime.
• Soft Skills:
  
  Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups.

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community.

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