Vice President Clinical Operations - Oncology

Vice President of Clinical Operations – Oncology

Department: Oncology Clinical Operations

Reports To: Chief Operating Officer (COO)

Location: West-Coast Preferred (Travel throughout all Oncology clinics required)

The Vice President of Clinical Operations – Oncology is responsible for providing strategic leadership, operational oversight, and clinical excellence across Helios Clinical Research's oncology research sites throughout initially California, Florida and Arizona with expansion planned into other states. This executive leader drives operational performance, ensures regulatory compliance, supports business growth, and partners closely with physicians, sponsors, CROs, and executive leadership to deliver high-quality clinical research while maintaining exceptional patient care.

The Vice President serves as a key member of the executive leadership team, developing scalable operational strategies that support Helios' mission of advancing oncology research through innovation, quality, and operational excellence.

• Provide strategic leadership and direction for all oncology clinical operations.
• Develop and execute operational strategies aligned with organizational goals.
• Foster a culture centered on patient safety, quality, accountability, and continuous improvement.
• Serve as a trusted advisor to executive leadership regarding clinical operations and site performance.
• Lead organizational initiatives, change management efforts, and operational integrations.

• Oversee the day-to-day operations of multiple oncology research clinics.
• Ensure consistent execution of clinical research protocols while maintaining exceptional patient care.
• Establish operational standards and best practices across all Oncology sites.
• Monitor operational metrics including patient enrollment, study activation timelines, visit completion, protocol compliance, site productivity, and financial performance.
• Develop corrective action plans when operational goals are not achieved.
• Drive continuous improvement initiatives to increase efficiency and study performance.

• Partner closely with Principal Investigators and Sub-Investigators to ensure successful study execution.
• Build strong relationships with physician leadership and clinic management.
• Support physician engagement in new study opportunities.
• Resolve operational issues impacting patient care or study execution.
• Promote collaboration across physicians, coordinators, regulatory, pharmacy, laboratory, and business departments.

• Ensure compliance with FDA regulations, ICH-GCP Guidelines, Oncology requirements, sponsor requirements, IRB requirements, and company SOPs.
• Collaborate closely with Regulatory Affairs and Quality Assurance.
• Support FDA inspections, sponsor audits, and internal quality reviews.
• Implement corrective and preventive actions (CAPAs).
• Promote a culture of quality and regulatory excellence.

• Develop and manage operational budgets.
• Monitor clinic profitability and financial performance.
• Partner with Finance regarding revenue forecasting, staffing models, and operational efficiencies.
• Support business development efforts and evaluate operational feasibility of new opportunities.
• Assist in site expansion, acquisitions, and integration initiatives.

• Lead, mentor, and develop Directors, Site Operations Managers, Clinical Managers, and operational leaders.
• Establish performance expectations and accountability measures.
• Conduct performance evaluations and coaching.
• Support succession planning, recruitment, retention, and employee development.

Partner with Executive Leadership, Medical Directors, Principal Investigators, Regulatory Affairs, Quality Assurance, Human Resources, Finance, Business Development, Information Technology, Sponsors, and CROs to ensure operational excellence.

• Evaluate operational readiness for new oncology studies.
• Support expansion into new therapeutic areas.
• Assist with mergers, acquisitions, and integration of new research sites.
• Identify innovative technologies…