More jobs:
Downstream Scientist
Job in
Foster City, San Mateo County, California, 94420, USA
Listed on 2026-02-28
Listing for:
Integrated Resources, Inc ( IRI )
Full Time
position Listed on 2026-02-28
Job specializations:
-
Engineering
Research Scientist -
Healthcare
Job Description & How to Apply Below
Join our Biologics Pilot Lab and contribute directly to the development, scaleup, and pilot-scale production of early and late-stage biologic programs. In this role, you will execute downstream purification operations, support upstream activities as needed, and help advance programs that are central to Client biologics pipeline. This position is ideal for candidates who are hands-on in the lab, collaborative, and excited to work on fast moving development efforts.
Key Responsibilities Technical & Operational- Plan and execute downstream purification and scale-up activities including filtration, chromatography, and buffer preparation.
- Support upstream operations as needed to ensure seamless end-to-end process execution.
- Monitor, analyze, and interpret process and performance data; prepare clear summaries of findings as appropriate.
- Maintain laboratory readiness, including equipment maintenance, analytical instrument upkeep, consumable inventory management, and general lab support.
- Present data, results, and conclusions in group meetings and cross functional discussions.
- Communicate technical information clearly and effectively to colleagues at varying levels.
- Work with a team-oriented, collaborative, and solutions-focused mindset.
- Maintain a strong safety focus in all laboratories and pilot operations.
- Hands-on experience with downstream purification operations, including centrifugation, chromatography, TFF, and depth filtration.
- Proficiency with AKTA systems and UNICORN programming.
- Practical experience in chromatography column operations, including resin packing and unpacking at various scales (e.g. 4.4 to 30 cm internal diameter columns).
- Strong verbal communication, technical writing, and documentation skills.
- Ability to work effectively in cross functional teams and in a dynamic environment.
- Self-motivated, organized, and comfortable with scientific problem solving.
- Experience in pilot plant operations for biologics in a single-use facility.
- Familiarity with Process Development and/or current Good Manufacturing Practices (cGMP), technology transfer, plant operations, and bioprocess scaleup principles.
AA/AS degree with 2+ years of relevant industry experience (purification techniques), or
BS/BE in Chemical/Biochemical Engineering, Biochemistry, Biology, or related discipline with 1+ year of relevant experience.
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