Senior Manager, Commercial IT Integration Lead

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

The Senior Manager, Commercial IT Integration Lead is responsible for owning and operating Mirum’s Commercial IT integration landscape, serving as the enterprise lead for data movement, system connectivity, and integration governance.

This role has end-to-end accountability for the stability, scalability, monitoring, and continuous improvement of real-time, event-driven, and batch data flows supporting Salesforce Life Sciences Cloud (SFLC) and the broader Commercial ecosystem.

As the Patient CRM platform transitions to steady state, this role will expand to support broader Commercial IT integration strategy and data movement initiatives to strengthen Mirum’s enterprise data foundation. The Senior Manager, Commercial Integration Lead partners closely with the CRM Platform Lead, internal IT teams, business users, and external vendors to ensure integrations and data flows are reliable, scalable, and supportable in a regulated environment.

• Serve as the IT owner for Commercial integrations, with accountability for enterprise integration architecture, standards, and governance.
• Define and enforce reusable integration patterns, API strategies, data contracts, and architectural guardrails across Commercial systems.
• Own the reliability, scalability, performance, and resiliency of real-time, event-driven, and batch integrations across Salesforce and external platforms.
• Partner closely with the CRM Platform Lead to ensure tight alignment between platform configuration, integration design, and data flow behavior.
• Contribute to long-term Commercial IT integration and data architecture strategy as the ecosystem matures.
• Integration Operations & Monitoring
• Establish proactive monitoring, alerting, health metrics, and observability frameworks across all Commercial integrations.
• Lead incident management, root cause analysis, and remediation for integration failures impacting Patient Services or HCP engagement operations.
• Design and implement structured error-handling, retry logic, and recovery patterns to minimize business disruption.
• Oversee integration change management, release coordination, and production support processes.
• Refine and standardize integration patterns to improve reliability, performance, and ease of troubleshooting, independent of specific tools.
• Partner with IT leadership to evaluate, select, and recommend integration technologies as business and scalability needs evolve.
• Support initiatives to centralize and operationalize Commercial data assets, ensuring integration patterns align with enterprise data engineering and warehousing strategies.
• Ensure integration solutions are operationally supportable, well-documented, and resilient regardless of the underlying platform.
• Work closely with internal IT teams, the SFLC Platform Lead, and external IT vendors to design, implement, and support integrations.
• Coordinate deployments, production support, and issue resolution across multiple vendors and system owners.
• Ensure effective knowledge transfer from implementation vendors to internal IT teams for long-term ownership.
• Governance, Security & Compliance
• Ensure integrations comply with Mirum’s security, data privacy, and regulatory requirements, including controlled data handling.
• Support audit readiness by maintaining integration documentation, data flow diagrams, and operational procedures.
• Implement and enforce governance practices for integration design, change management, and production support.
• Identify opportunities to improve automation, observability, and operational efficiency across the integration landscape.
• Document integration architectures, support processes, and troubleshooting guides to enable consistent operations.
• Support…