Head of Process Analytical Technology - Mammalian Platform

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* Job Title:

** Head of Process Analytical Technology - Mammalian Platform
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* Location:

** Framingham, MA
** About Sanofi:
** We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
** About the Job
** Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

The Mammalian Platform (part of Sanofi R&D) is responsible for the development, scale-up, and transfer of upstream and downstream processes and their control strategies for clinical and commercial manufacturing of therapeutic proteins produced from mammalian cell lines. In addition, the department actively invests in developing and implementing new technologies related to integrated and continuous biomanufacturing, process analytical technology (PAT), high throughput process development, and modeling.

Ultimately, our goal is to design robust processes that produce safe and effective medicines as efficiently as possible.

We are looking for candidates to lead our Process Analytical Technology activities across the Mammalian Platform including applications for both cell culture and purification processes. This individual should be able to combine innovation leadership skills with technical expertise to continuously evolve and lead teams in the delivery of our Process Analytical Technology roadmap. The incumbent will lead in a matrixed structure, leveraging resources across the platform’s global footprint in both the United States (Framingham, MA) and France (Vitry) while representing the platform at the interface with our Commercial Manufacturing and Supply (M&S) organization.

This role will report to the Global Head of Purification Development, providing a direct link to Mammalian Platform leadership to support sustained innovation and technology implementation in both clinical and commercial manufacturing applications.
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* Main Responsibilities:

*** Lead the development and implementation of Process Analytical Technology for the Mammalian Platform, including cell culture and purification applications
* Drive the design and evolution of our Process Analytical Technology roadmap to enable near-term implementation
* and* long-term disruptive innovation
* Represent the Mammalian Platform for PAT-related topics, interfacing with Commercial Manufacturing and Quality, as well as other Platforms within R&D (Microbial, Genomic Medicines, mRNA, Vaccines, Synthetics)
* Engage relevant stakeholders across R&D and Commercial Manufacturing to ensure resources, budget, and implementation risk are adequately managed and communicated
* Identify opportunities to improve our process development strategies and manufacturing approaches through the application of PAT
* Act as a PAT champion across the Sanofi R&D and Manufacturing network
* Mentor scientists across sites and teams fostering their career development and professional growth
** About You
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* Basic Qualifications:

*** PhD. in Biochemical Engineering, Chemical Engineering, Analytical Chemistry, Physics, Bioengineering, Electrical Engineering, or related fields with at least 7 years of experience or a M.S. with at least 11 years of relevant experience or a B.S. with at least 12 years of relevant experience
* Relevant industrial experience and/or academic experience in Process Analytical Technology development
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* Preferred Qualifications:

*** Experience with spectroscopic Process Analytical Technology (Raman, Near-Infrared, Mid-Infrared, Fluorescence, UV-Vis) techniques
* Experience with online or inline analyzers for Process Analytical Technology applications (HPLC, UPLC, LCMS, DLS, MALS) and auto-sampling techniques
* Understanding of PAT-enabling digital architecture and its application in manufacturing settings (SynTQ, SIMCA-Online, Distributed Control Systems)
* Familiarity with…