Senior Scientist – Critical Reagents

Description

We are seeking a highly skilled and motivated Senior Scientist specializing with Biochemistry/Chemistry background to join B2S Critical Reagents Team Umbrella. The ideal candidate will play a key role in diligent design, generation, and characterization of critical reagents directly to the advancement of large molecule bioanalytical pipelines.

The Senior Scientist I – Critical Reagents is responsible for the generation, characterization, and lifecycle management of custom critical reagents to support the development of robust, regulated bioanalytical assays for large-molecule biotherapeutics. Critical reagents include well-characterized polyclonal and monoclonal antibodies, recombinant proteins, conjugated proteins and peptides, gene therapy vectors, oligonucleotides, and critical reagent kits. This position offers an exciting opportunity to lead and collaborate within a multidisciplinary scientific environment, contributing to innovation, assay robustness, and scientific excellence across the development lifecycle of large-molecule biotherapeutics.

• Serves as a Scientist/Principal Scientist for clients’ projects.
• Performs a variety of protein conjugation chemistry, protein purification activities and downstream biochemical/bioanalytical and biophysical characterization methodologies.
• Able to design, execute, trouble shoot experiments associated with critical reagents generation and /or characterization with minimum supervision.
• Compiles scientific data (including analysis and technical writing) and able to present data in an intelligible format suitable for a professional audience.
• Able to train junior level scientists.
• Reports and treats data with prominent level of integrity and ethics.
• Complies with applicable regulations (GXP); maintains proper records in accordance with standard operating procedures (SOPs) and policies; independently designs and performs scientific experiments with a pre-defined goal including developing new methodologies, protocols, and/or test procedures that contribute to core group research goals and reflect expert knowledge.
• Independently apply basic scientific principles, performs literature searches, attends scientific meetings, and keeps up to date on literature in the biotherapeutic bioanalysis field.
• Maintains laboratory equipment, as needed.
• Other duties as assigned.

• Quality and Quantity – Demonstrates accuracy and thoroughness; looks for ways to improve and promote quality; applies feedback to improve performance; monitors own work to ensure quality; meets productivity standards; completes work in timely manner; strives to increase productivity; works quickly but efficiently.
• Analytical – Synthesizes complex or diverse information; collects and researches data; uses intuition and experience to complement data; designs workflows and procedures.
• Safety and Security – Observes safety and security procedures; determines appropriate action beyond guidelines; reports potentially unsafe conditions; uses equipment and materials properly.
• Problem Solving – Identifies and resolves problems in a timely manner; gathers and analyzes information skillfully; develops alternative solutions; works well in group problem solving situations; uses reason even when dealing with emotional topics.
• Oral and Written Communication – Speaks clearly and persuasively in positive or negative situations; listens and gets clarification; responds well to questions; demonstrates group presentation skills; participates in meetings.

• Ph.D. degree in biochemistry, chemistry or related discipline with related experience in biology/chemistry techniques is required.
• M.S. degree in biochemistry, chemistry or a related discipline, 10+ years with related experience in biology/chemistry techniques is required.

• Hands‑on experience with protein purification methodologies using various chromatography techniques.
• Proficiency in basic protein characterization techniques such as ELISA, SDS-PAGE, analytical chromatography techniques (SEC, NP/RP – HPLC, ion exchange methodologies).
• Optional Technical
  
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  Experience or familiarity with…