Postdoctoral Fellowship-Immunology

Position Overview

Tonix Pharmaceuticals is a commercial stage biotechnology company focused on CNS and immunology treatments. We are seeking a highly motivated and innovative Postdoctoral Fellow with a background in immunology, autoimmunity or oncology to contribute to research and development across our growing immunology portfolio. This is an excellent opportunity to directly participate and obtain exposure to the end‑to‑end product development process including early‑stage therapeutic discovery, nonclinical safety and pharmacological evaluation, cGMP manufacturing and clinical evaluation.

The candidate will have a recent Ph.D. or M.D./Ph.D. in a relevant field, a strong publication record, and experience working in an interdisciplinary team environment. The position is located at the Tonix Research and Development Center (RDC), the innovation and development arm of Tonix Pharmaceuticals. The RDC houses state‑of‑the‑art equipment (high‑content imaging, mass spectrometry, spectral flow cytometry, in vivo imaging system, multi‑parallel bioreactors, etc.)

and is responsible for the development of efficient and cutting‑edge treatment methods. The individual in this position will work as part of the research team to deliver and optimize therapeutic pipelines for potential clinical investigation. This position will report to the Director of Immunology and will be based at the Tonix Research and Development Center in Frederick, Maryland.

• Conduct independent and original research supporting the Tonix portfolio and RDC mission
• Develop novel methods and assays to contribute to the RDC research pipeline
• Establish in‑vitro and in‑vivo models to support evaluation of immunotherapeutics against diverse disease conditions (e.g., oncology, autoimmunity)
• Collect, analyze, and evaluate data
• Interpret data, make decisions, and troubleshoot related technical issues
• Prepare scientific presentations, reports, manuscripts, and grant proposals
• Design, optimize, and standardize novel in‑house assays ensuring consistent reliability and reproducibility of screening outcomes
• Provide scientific leadership and expertise in cell‑based, molecular, and biochemical assays while ensuring rigorous experimental data analysis
• Independently troubleshoot, problem‑solve, and execute experiments while incorporating feedback and adapting to evolving project needs
• Work cross‑functionally in a matrix environment, partnering with project and functional teams to drive research objectives forward
• Characterize and assess binding properties of novel proteins and antibodies using cutting‑edge technologies, including Octet, high‑content plate‑based imaging, and novel reporter‑based assays
• Perform antibody and protein engineering, including affinity maturation, to optimize potency and therapeutic potential
• Lead and participate in cross‑functional project teams, proposing innovative discoveries and optimization strategies that align with industry’s best practices
• Integrate cross‑functional inputs to develop a robust, strategic R&D plan, ensuring alignment with Tonix’s innovation goals

• Ph.D. or equivalent doctoral degree
• Strong record of independent, high‑quality, creative, and impactful research in viral vector application as vaccines against deadly pathogens and antibody or protein design and discovery
• Ability to generate hypotheses, use data sets to evaluate them, and design new studies
• Experience applying multiple cutting‑edge techniques for drug screening such as high‑content imaging, microscopy, and cell‑based screening
• Experience in industry or biological context with ability to interrogate large data sets using computational tools and bioinformatics to dissect complex data sets such as high‑throughput data
• Ability for minimal travel
• Dedicated team player who can withstand the high demands of a fast‑paced environment
• Excellent written and verbal communication skills
• Strong planning and organizational skills
• Comfortable working independently with minimal supervision
• Highly organized, results‑driven, problem‑solver, and collaborator
• Demonstrated ability to perform the essential duties of the position with or without…