Research Associate Supervisor

Research Associate Supervisor

Job
Employee Type: exempt full-time
Division:
Vaccine, Immunity and Cancer Directorate
Facility:
Frederick: ATRF

Location:

8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

The Vaccine, Immunity and Cancer Directorate (VICD) has a primary mission to provide scientific leadership and laboratory infrastructure to study immune responses to Human Papillomavirus (HPV) vaccines and other cancer preventive strategies in the context of preclinical and clinical studies. As part of a large effort, the National Institute of Allergy and Infectious Diseases (NIAID) and the Frederick National Laboratory (FNL) and other stakeholders are developing vaccines with durable protection for seasonal influenza virus.

VICD is leading the development of immunoassays with the highest reproducibility, sensitivity, and specificity for evaluation of immune responses against the virus and vaccine.

VICD is recruiting for a Research Associate Supervisor to work in a fast-paced, high impact laboratory within an internationally recognized research directorate. The aim of this project is to generate standardized sets of reagents, develop assays for assessment of antibody responses to HPV and conduct high throughput immunogenicity testing of vaccines in the context of clinical trials, under the Good Clinical Laboratory Practices.

This position is primarily in the laboratory conducting testing and onsite activities.

We are seeking an individual with a strong background in molecular biology and immunology to work at the HPV Serology Laboratory to lead projects in the area of vaccine immunogenicity. The aim of this project is to generate standardized sets of reagents, develop assays for assessment of antibody responses to HPV and conduct high throughput immunogenicity testing of vaccines in the context of clinical trials.

This position is not eligible for telework.

• Perform tissue culture and immunological/virological techniques, including aseptic techniques, cell line maintenance, production of plasmids and virus-like particles
• Oversee serology projects from conception to execution
• Responsible for sample management
• Optimize and validate procedures and methodologies for assessment of immune responses to infection and vaccines
• Plan experiments and lead testing of large number of samples from clinical studies
• Design and implement protocols, as well as troubleshoot assays and experiments independently
• Evaluate, analyze and compile data, maintain databases
• Responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment and inventories
• Prepare reports, present data and participate in report and proposal preparation
• Remain current on literature and relevant laboratory techniques
• May supervise lab personnel

• Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
• In addition to the education requirement, a minimum of four (4) years of progressively responsible experience, including one (1) year of experience in a leadership/manager capacity
• Detailed knowledge of vaccines, immunology, and virology
• Experience in cellular and molecular biological techniques, including tissue culture, including aseptic techniques, cell line maintenance, production of plasmids and virus-like particles, western-blot, virus neutralizing assays, plaque assays, and PCR
• Demonstrates current knowledge of emerging relevant scientific literature and immune profiling technologies
• Ability to ensure assay rigor, reproducibility, and compliance with…