Sr. Research Associate, Analytical Development

Theradaptive is revolutionizing the field of therapeutic delivery with a pipeline of best-in-class products that address multiple global markets. Theradaptive is performing cutting edge science in the area of regenerative medicine, working at the interface of Biology and Orthopedic tissue repair.

Our lead therapeutics are in the following indications:

• Spinal Fusion
• Dental and Facial Bone Repair

We are an innovative, fast-paced team that is advancing a diverse array of cutting‑edge translational research projects.

Theradaptive, a pioneering biotech company specializing in regenerative medicine, seeks a motivated Research Associate to join our Analytical Development team. The successful candidate will be instrumental in supporting the development, troubleshooting, and execution of assays utilizing chromatography, electrophoresis, and immunoassay techniques. This role will contribute significantly to the characterization and quality assessment of Biologic Drug Substances and Drug Product/Medical Devices.

• Assist in the development and optimization of analytical methods using Chromatography (SEC-HPLC, RP-HPLC), moisture/water content determination (including Karl Fisher), and/or electrophoresis (cIEF, CE‑SDS) techniques for the release and characterization of biologics and drug product/medical devices.
• Execute laboratory experiments, including sample testing and characterization of biologics using chromatography, UV spectroscopy, electrophoresis, and/or immunoassay and cell‑based assays.
• Perform sample testing, analyze data, interpret results, and contribute to the preparation of reports in various formats, including Laboratory Notebooks (LN), formal reports, and presentations.
• Assist in the creation and review of Standard Operating Procedures (SOPs) for test method procedures and laboratory equipment operation and execute method qualification and validation studies.
• Ensure proper qualification, calibration, and maintenance of laboratory equipment in accordance with established schedules.
• Adhere to cGMP requirements as necessary and uphold compliance with standard operating procedures to maintain quality standards.
• Collaborate effectively within a team environment, demonstrate attention to detail, and communicate effectively verbally and in writing.
• Use standard laboratory, data analysis, and GMP quality systems, including Excel, Graph Pad Prism, Laboratory Notebooks (LN), instrument software, and electronic quality systems, to support analytical development, testing, data review, investigations, trending, and compliant documentation.
• Adherence to laboratory and workplace safety protocols, proper use of personal protective equipment (PPE), hazard identification and reporting, and comply with the company’s safety policies.
• Undertake any additional duties and responsibilities as needed to support the objectives of the laboratory.

• Bachelor's or Master's degree in Biochemistry, Pharmaceutical Analysis, Biotechnology, or Analytical Chemistry.
• Bachelor's degree with at least 5 years or Master's degree with at least 3 years of industry laboratory experience.
• Hands‑on experience with Chromatography (SEC‑HPLC, RP‑HPLC) and/or electrophoresis (cIEF, CE‑SDS) techniques.
• Strong multitasking abilities, effective time management skills, and excellent organizational capabilities.
• Ability to work collaboratively in a team environment, with meticulous attention to detail.

• Ability to work in a laboratory and office setting full time.
• Ability to lift up to 40 lbs.
• Ability to work in a laboratory with chemicals and biochemicals and perform Biosafety Level 2 work

• Theradaptive corporate headquarters and laboratory in Frederick, MD.

$94,000 – $102,000 annually, based on qualifications and level.

Theradaptive is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, ethnic or national origin, ancestry, pregnancy (including childbirth or related condition), citizenship, familial status, mental or physical disability, veteran status, genetic information, other non‑disqualifying disability, or any other characteristic protected by law.