Supervisor, Research Associate

Job
Employee Type: exempt full-time
Division:
Vaccine, Immunity and Cancer Directorate
Facility:
Frederick: ATRF

Location:

8560 Progress Dr, Frederick, MD 21701 USA
The Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

The Vaccine, Immunity and Cancer Directorate (VICD) has a primary mission to provide scientific leadership and laboratory infrastructure to study immune responses to Human Papillomavirus (HPV) vaccines and other cancer preventive strategies in the context of preclinical and clinical studies. As of recent and part of a large effort, the National Institute of Allergy and Infectious Diseases (NIAID) and the Frederick National Laboratory (FNL) and other stakeholders are evaluating new vaccines with durable protection for influenza virus.

VICD is leading the development of immunoassays with the highest reproducibility, sensitivity, and specificity for evaluation of immune responses against the virus and vaccine. VICD is recruiting for a Lead, Research Associate to work in a new high impact laboratory that will develop and implement validated immunoassays to be utilized in clinical trial studies, within an internationally recognized research directorate.

The ideal candidate will have prior experience working under the Good Clinical Laboratory Practices, with deep understanding of the immunology of influenza viruses or other respiratory viruses, infections and vaccines. This role offers a unique opportunity to shape new scientific directions within a mission-driven environment that integrates new assay development, translational research and clinical evaluation of new preventive strategies.

The Vaccine, Immunity, and Cancer Directorate (VICD) is recruiting for a Lead/Supervisor, Research Associate, reporting to the Scientific Manager, assisting with managing a laboratory team and support the development, standardization, and validation of multiple new serology and cellular immunity assays, and conduct sample testing for critical trials. This position is a laboratory position.

• Oversee laboratory projects from conception to execution
• Develop and validate Multiplex based assays by Luminex or other platform and Antibody Dependent Cytotoxicity Assays
• Responsible for sample management and inventory using laboratory information management systems (LIMS)
• Develop, optimize, and validate procedures and methodologies for assessment of immune responses to infections and vaccines
• Plan experiments and conduct testing of large number of samples from clinical studies, support Scientific Manager in scheduling staff for testing
• Design and implement protocols (literature searches as required), as well as troubleshoot assays and experiments independently and assist laboratory staff to advance the experiments or studies
• Evaluate, analyze and compile large sets of data using data analysis software (or other scripts such as R or Python, etc.), and maintain databases
• Responsible for routine QC/QA procedures and maintaining equipment under
• Good Clinical Laboratory Practices
• Manage laboratory supplies and inventory, ensuring minimal impact to workflow
• Prepare reports, present data and participate in report and proposal preparation
• Contribute or write SOPs or protocols in Master Control
• Utilize Laboratory Information Management System (LIMS) for laboratory operation
• Remain current knowledge of emerging relevant scientific literature and immune profiling technologies and laboratory techniques
• Ensures assay rigor, reproducibility, and compliance with GCLP/GLP standards where applicable
• Other duties as assigned

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of Master’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or six (6) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
• In addition to the education requirement, a minimum of four (4) years of progressively responsible experience, including one (1) years of…