Director, Site Operations/Project Portfolio Management - PMO
Listed on 2026-03-01
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Management
Operations Manager, Program / Project Manager
Introduction to role
Are you ready to steer a high-impact infrastructure capital project portfolio that enables our science, strengthens our manufacturing, and ultimately helps deliver medicines to patients faster and more safely? Do you thrive at the intersection of strategy, execution, and cross-functional leadership, turning complex portfolios into transparent, data-driven decisions?
As Director, Project Portfolio Management, you will lead the site Operations PMO and shape how capital and infrastructure investments are prioritized and delivered across both GMP and non-GMP environments. Your leadership will connect project outcomes to business goals, balancing quality, safety, speed, and sustainability. You will bring discipline and clarity to a dynamic environment, establishing governance, elevating standards, and empowering teams to perform at their best.
This is a role for a bold, practical leader who can set direction, coach teams, and make tough choices with confidence. You will champion a culture of continuous improvement, using digital tools and transparent metrics to reduce risk, improve predictability, and unlock capacity for our long‑term site strategy.
Accountabilities- PMO Leadership and Strategy:
Provide strategic leadership and direction to the Site Operations PMO, overseeing all capital and infrastructure projects across GMP and non‑GMP portfolios to deliver against site and enterprise objectives. - Governance and Standards:
Develop, implement, and maintain PMO governance frameworks, project management standards, and reporting tools that drive consistency, quality, and compliance across the portfolio. - People Leadership:
Lead a team of Project Managers and Project Engineers, set clear performance expectations, manage workload, and support professional development to build a high‑performing PMO. - Portfolio Prioritization and Resource Planning:
Oversee portfolio prioritization, resource planning, and execution to ensure projects align with business objectives and capital investment strategy, maximizing value and minimizing disruption. - Financial Stewardship:
Partner with Finance to manage multi‑year capital budgets, forecasts, and expenditure tracking, ensuring accurate visibility and alignment with long‑term site investment planning. - Performance Transparency:
Establish and maintain portfolio‑level dashboards, KPIs, and reports that provide clear, timely transparency to senior leadership and enable data‑informed decision‑making. - Risk, Change, and Issue Management:
Drive rigorous risk management, change control, and issue resolution across the portfolio, ensuring timely mitigation and escalation to protect schedule, cost, and quality. - Cross‑Functional Compliance:
Collaborate with Engineering, Quality, SHE, and Procurement to ensure projects meet technical, safety, and regulatory requirements from design through handover. - Audit and Inspection Readiness:
Ensure readiness for audits and inspections through robust documentation, quality control, and adherence to governance. - Innovation and Continuous Improvement:
Champion innovation and continuous improvement across the PMO by leveraging digital tools, benchmarking, and lessons learned to enhance predictability and performance. - Culture and Ways of Working:
Foster a culture of collaboration, accountability, and operational excellence across all functions involved in project delivery, modeling behaviors that elevate quality and safety alongside speed. - GMP Portfolio Oversight:
Oversee the GMP project portfolio supporting manufacturing, QC, and analytical spaces, ensuring full regulatory compliance and audit readiness; collaborate with Quality and Validation to maintain a state of control; ensure technical governance for GMP utilities, controlled environments, and validated systems. - Non‑GMP Portfolio Oversight:
Oversee the non‑GMP project portfolio including research, vivarium, and office environments; partner with Workplace Services and Lab Ops to enable long‑term site strategy and capacity growth; implement sustainability and energy efficiency standards within project delivery to support Ambition Zero Carbon objectives.
- Bachelor’…
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