Director, Global Commercial, HER-ADC

At AstraZeneca, we are changing the way cancer is treated through science, innovation, and a deep commitment to patients. Our ambition in Oncology is bold: to redefine cancer care, transform outcomes, and bring life-changing medicines to people around the world.

As one of the fastest-growing areas of our business, Oncology combines a world-class pipeline, market-leading brands, and a relentless focus on scientific advancement. Joining this team means working at the forefront of one of the most dynamic and meaningful areas in healthcare.

We are looking for a Director, Global Commercial, HER2-ADC to join our Global Oncology Franchise Team in Gaithersburg, MD. This is a high-impact global role for an experienced commercial leader whose strongest asset is brand strategy and who thrives in shaping growth beyond a single indication. You will help define how HER2 ADC evolves across tumor types, lead pan-tumor initiatives, shape above-brand strategy, and influence the commercial choices that will shape the brand's future.

You will partner closely with global indication leads, cross-functional colleagues, regional leads and markets.

The ideal candidate combines strategic thinking with strong execution discipline and will play a central role in shaping the brand's long-term commercial direction. This role is particularly well suited to someone who is energized by enterprise-level brand strategy and skilled at bringing diverse stakeholders together around a shared ambition.

Working across the organization, you will translate scientific opportunities, customer insights, and evolving market dynamics into clear strategic choices that drive sustainable growth and improve outcomes for patients.

• Lead competitive readiness efforts around emerging threats, monitoring the fast-evolving landscape across indications and translating developments into actionable commercial implications.
• Play a key role in developing cross-functional lifecycle strategies to maximize the brand's value throughout its lifecycle and prepare for the transition to post-exclusivity competition.
• Develop key strategic presentations for leadership

• Drive key elements of the above-indication Brand Strategy Plan, developing strategic content and building alignment across a broad cross-functional network (Market Access, Medical, Diagnostics, regional leads).
• Ensure seamless execution of key cross-indication initiatives and asset delivery
• Shape the evolution of the brand positioning and narrative, to solidify leadership in a rapidly evolving oncology landscape.

• Design and implement an innovative market engagement model, leveraging new technologies to enable ongoing dialogue with markets and accelerate the sharing and adoption of best practices across countries.
• Optimize engagement with key external experts across indications, ensuring insights are systematically captured, synthesized, and translated into commercial priorities and actions.

• Bachelor's degree in a relevant field, preferably in a scientific or business discipline.
• 5+ years of experience in the pharmaceutical and/or healthcare industry across brand marketing, sales, market research or analytics, strategic planning, or related commercial roles.
• Strong marketing experience, including brand strategy, positioning, messaging, segmentation, targeting, agency management and annual planning.
• Experience in oncology marketing, with global launch or lifecycle management experience preferred.
• Demonstrated ability to translate complex scientific and market information into clear commercial implications and action.
• Strong project leadership skills and the ability to manage multiple priorities in a matrixed environment.
• Demonstrated ability to lead without authority and influence across functions, markets and teams.
• Strong clinical acumen, scientific curiosity and commercial judgement.
• Entrepreneurial mindset, comfort with ambiguity and a track record of improving ways of working.

• Prior oncology marketing experience, ideally in breast cancer or another solid tumor setting.
• Experience working across global, regional and local market teams.
• Experience across personal, non-personal, digital and patient-focused channels.
• Sales or customer-facing experience.
• MBA or advanced degree in a related field
• Experience working in a commercial…