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Principal Scientist, Primary Pharmacology - Hit ID & Lead

Job in Groton, New London County, Connecticut, 06349, USA
Listing for: Pfizer
Full Time position
Listed on 2026-08-12
Job specializations:
  • Research/Development
    Research Scientist
  • Healthcare
Salary/Wage Range or Industry Benchmark: 106000 - 177000 USD Yearly USD 106000.00 177000.00 YEAR
Job Description & How to Apply Below

Pfizer in Groton, CT is seeking a Principal Scientist in Primary Pharmacology to accelerate hit identification and lead optimization for small molecule drug discovery. You will design and run in vitro assays, study target engagement, and work with biology, chemistry, and computational teams to advance early discovery projects.

The role requires a PhD with substantial pharmacology experience, strong hands-on assay skills (HTRF/ELISA/FP/BRET), and a collaborative mindset to deliver impact across

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