Associate Scientist

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Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life‑threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T‑cell, T‑cell receptor (TCR‑T), and natural killer (NK) cell‑based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting‑edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialise ciltacabtagene autolecuel (cilta‑cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking Associate Scientist as part of the Global MSAT team based in Somerset, NJ
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We are seeking a motivated Associate Scientist to join our MSAT team, supporting the development, troubleshooting and optimisation of automated manufacturing processes for CAR‑T and other cell therapy products. Under the guidance of senior staff, this role will perform bio‑pilot run experiments, technology evaluations and process improvement studies. The position will directly contribute to manufacturing robustness and efficiency by executing laboratory work, assisting in equipment testing and analysing process data.

• Execute bench‑scale experiments for bio‑pilot run comparisons, technology evaluations and process improvement initiatives.
• Operate and assist in troubleshooting closed‑system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G‑Rex).
• Perform and support analytical assays such as flow cytometry, qPCR, ELISA, and cell counting to evaluate product quality and process outcomes.
• Collect, analyse and summarise experimental data (cell growth, viability, metabolite trends) using statistical tools.
• Support preparation of study protocols, technical reports and SOPs in compliance with GMP standards.
• Assist in process troubleshooting and root‑cause investigations for manufacturing and automation systems.
• Maintain a safe, organised and compliant laboratory workspace.
• The role makes independent decisions regarding routine laboratory execution, minor troubleshooting and data analysis within approved study protocols. Guidance is sought from senior team members for experimental design, major troubleshooting steps and changes to validated processes.

• Bachelor’s degree in biotechnology, bioengineering, molecular biology or related discipline.
• 1–2 years of hands‑on cell culture (T‑cells, immune cells or primary cells) experience in academic, process development or GMP labs.
• Hands‑on experience with aseptic technique and biosafety cabinet work.
• Experience in basic analytical methods such as cell counting, viability assays and metabolite monitoring.
• Familiarity with data analysis and preparation of technical documentation.
• Exposure to automated/closed‑system platforms preferred.
• Strong organisational and documentation skills.
• Proficiency with Microsoft Office (Excel, Word, PowerPoint).
• Basic data analysis using Excel, JMP or similar tools.
• Ability to interface with instrument control software.

The anticipated base pay range is $81,273 - $106,669 USD.

We are committed to creating a workplace where employees can thrive – both professionally and personally. To attract and retain top talent, we offer a best‑in‑class benefits package that supports well‑being, financial stability and long‑term career growth. Highlights include medical, dental and vision insurance; a 401(k) retirement plan with company match that vests fully on day one; equity and stock options available to employees in eligible roles;

eight weeks of paid parental leave after just three months of employment; a paid time‑off policy that includes 15 vacation days, 5 personal days, 5 sick…