Postdoc in Genetic Kidney Disease at Harvard Medical School

Overview

University:
Harvard Medical School

Country: USA

Deadline:
Not specified

Fields: cell biology, molecular biology, genetics, physiology, nephrology

Topic: USA – Postdoc in Genetic Kidney Disease at Harvard Medical School

Position: postdoc

Main Category: life & medical sciences

Are you passionate about advancing our understanding of genetic diseases and eager to contribute to groundbreaking research that could transform pediatric medicine? If you are seeking a postdoctoral opportunity to deepen your expertise in kidney biology and rare disease research, the Majmundar Lab at Harvard Medical School and Boston Children’s Hospital offers an exceptional environment to launch the next phase of your scientific career.

Harvard Medical School, located in Boston, Massachusetts, is a leading institution for medical education, clinical care, and biomedical research. Boston Children’s Hospital, affiliated with Harvard Medical School, is recognized for pioneering pediatric research and patient care. The collaborative environment fosters interdisciplinary research with access to core facilities and a network of experts. Living in Boston provides exposure to a vibrant academic community and scientific innovation.

The Majmundar Lab focuses on pathogenic mechanisms underlying genetic kidney diseases, with emphasis on monogenic nephrotic syndrome (NS) and focal segmental glomerulosclerosis (FSGS). These conditions contribute to chronic kidney disease in children and can lead to end-stage renal failure. The lab leverages genomics, cell biology, proteomics, and disease models to identify molecular pathways and translate discoveries into therapeutic strategies for NS and related disorders.

• Investigate downstream signaling pathways of NOS1AP in podocyte biology using in vitro and in vivo models.
• Use mouse models and podocyte culture systems to determine protective roles of candidate proteins in NS/FSGS.
• Develop and employ induced pluripotent stem cell (iPSC)-derived kidney organoids as parallel models for disease study and therapeutic evaluation.
• Work in a collaborative, mentorship-rich lab environment with opportunities to present research at institutional and national forums.
• Position is multi-year, with potential for extension through successful grant applications.

• A recent PhD or MD (with substantial research experience) in cell biology, molecular biology, genetics, physiology, or a closely related field.
• Hands-on expertise in mammalian cell culture and molecular biology techniques (e.g., western blotting, immunofluorescence, cloning, qPCR).
• Experience working with mouse models of human disease.
• Strong publication record, including conference presentations.
• Excellent written and verbal communication skills; ability to work independently and in a team.
• Preferred: experience with iPSC culture and differentiation (renal or organoid systems), CRISPR/Cas9 gene editing, and background in kidney biology, genomics, proteomics, or rare disease research.

To apply, prepare: CV, a cover letter detailing research experience and interest in the Majmundar Lab, contact information for three references, two relevant publications from prior graduate studies. Submit materials per the official advertisement. This opportunity is advertised by Dr. Amar J. Majmundar and associated with Harvard Medical School and Boston Children’s Hospital.

• Comprehensive Guide to Graduate Final date to receive applicationss for US Universities (Fall 2026 Intake)
• Germany – PhD in Experimental Single-Cell Genomics at Helmholtz Munich
• Netherlands – Postdoc in Genetic Variance at Wageningen University
• USA – Fully Funded PhD in Kinesiology at University of Texas at Arlington
• Sweden – PhD in Medical Science (RNA-modifications & Cancer Biology) at University of Gothenburg

Conclusion:
This is a unique opportunity to join a leading research group at the intersection of genetics, kidney biology, and translational medicine. If you are driven to make a meaningful impact in pediatric health and advance your scientific career in a world-class environment, consider applying to the Majmundar Lab at Harvard Medical School and Boston Children’s Hospital.